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dc.contributor.authorDeng, Peigang
dc.contributor.authorLee, Yi-Kuen
dc.contributor.authorLin, Ran
dc.contributor.authorZhang, Tong-Yi
dc.date.accessioned2016-02-25T13:50:43Z
dc.date.available2016-02-25T13:50:43Z
dc.date.issued2012-07-30
dc.identifier.citationDeng P, Lee Y-K, Lin R, Zhang T-Y (2012) Nonlinear electro-mechanobiological behavior of cell membrane during electroporation. Applied Physics Letters 101: 053702. Available: http://dx.doi.org/10.1063/1.4739940.
dc.identifier.issn0003-6951
dc.identifier.doi10.1063/1.4739940
dc.identifier.urihttp://hdl.handle.net/10754/598990
dc.description.abstractA nonlinear electroporation (EP) model is proposed to study the electro-mechanobiological behavior of cell membrane during EP, by taking the nonlinear large deformation of the membrane into account. The proposed model predicts the critical transmembrane potential and the activation energy for EP, the equilibrium pore size, and the resealing process of the pore. Single-cell EP experiments using a micro EP chip were conducted on chicken red blood cells at different temperatures to determine the activation energy and the critical transmembrane potential for EP. The experimental results are in good agreement with the theoretical predictions. © 2012 American Institute of Physics.
dc.description.sponsorshipThis research was partially supported by a Hong Kong RGC grant (No. 615907) and by an award from the King Abdullah University of Science and Technology (KAUST Award No. SA-C0040/UK-C0016).
dc.publisherAIP Publishing
dc.titleNonlinear electro-mechanobiological behavior of cell membrane during electroporation
dc.typeArticle
dc.identifier.journalApplied Physics Letters
dc.contributor.institutionWuhan Institute of Technology, Wuhan, China
dc.contributor.institutionHong Kong University of Science and Technology, Hong Kong, China
kaust.grant.numberSA-C0040/UK-C0016
dc.date.published-online2012-07-30
dc.date.published-print2012-07-30


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