Modelling Aedes aegypti mosquito control via transgenic and sterile insect techniques: Endemics and emerging outbreaks

Type
Article

Authors
Seirin Lee, S.
Baker, R.E.
Gaffney, E.A.
White, S.M.

KAUST Grant Number
KUK-C1-013-04

Date
2013-08

Abstract
The invasion of pest insects often changes or destroys a native ecosystem, and can result in food shortages and disease endemics. Issues such as the environmental effects of chemical control methods, the economic burden of maintaining control strategies and the risk of pest resistance still remain, and mosquito-borne diseases such as malaria and dengue fever prevail in many countries, infecting over 100 million worldwide in 2010. One environmentally friendly method for mosquito control is the Sterile Insect Technique (SIT). This species-specific method of insect control relies on the mass rearing, sterilization and release of large numbers of sterile insects. An alternative transgenic method is the Release of Insects carrying a Dominant Lethal (RIDL). Our objective is to consider contrasting control strategies for two invasive scenarios via SIT and RIDL: an endemic case and an emerging outbreak. We investigate how the release rate and size of release region influence both the potential for control success and the resources needed to achieve it, under a range of conditions and control strategies, and we discuss advantageous strategies with respect to reducing the release resources and strategy costs (in terms of control mosquito numbers) required to achieve complete eradication of wild-type mosquitoes. © 2013 Elsevier Ltd.

Citation
Seirin Lee S, Baker RE, Gaffney EA, White SM (2013) Modelling Aedes aegypti mosquito control via transgenic and sterile insect techniques: Endemics and emerging outbreaks. Journal of Theoretical Biology 331: 78–90. Available: http://dx.doi.org/10.1016/j.jtbi.2013.04.014.

Acknowledgements
S.S.L. was partially funded by the Japan Society for the Promotion of Science (JSPS Excellent Young Researcher Overseas Visit Program and Grant-in-Aid for JSPS Young Researcher). This publication was based on work supported in part by Award No KUK-C1-013-04, made by King Abdullah University of Science and Technology (KAUST).

Publisher
Elsevier BV

Journal
Journal of Theoretical Biology

DOI
10.1016/j.jtbi.2013.04.014

PubMed ID
23608633

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