Modeling the Mechanical Response of In Vivo Human Skin Under a Rich Set of Deformations
KAUST Grant NumberKUK-C1-013-04
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AbstractDetermining the mechanical properties of an individual's skin is important in the fields of pathology, biomedical device design, and plastic surgery. To address this need, we present a finite element model that simulates the skin of the anterior forearm and posterior upper arm under a rich set of three-dimensional deformations. We investigated the suitability of the Ogden and Tong and Fung strain energy functions along with a quasi-linear viscoelastic law. Using non-linear optimization techniques, we found material parameters and in vivo pre-stresses for different volunteers. The model simulated the experiments with errors-of-fit ranging from 13.7 to 21.5%. Pre-stresses ranging from 28 to 92 kPa were estimated. We show that using only in-plane experimental data in the parameter optimization results in a poor prediction of the out-of-plane response. The identifiability of the model parameters, which are evaluated using different determinability criteria, improves by increasing the number of deformation orientations in the experiments. © 2011 Biomedical Engineering Society.
CitationFlynn C, Taberner A, Nielsen P (2011) Modeling the Mechanical Response of In Vivo Human Skin Under a Rich Set of Deformations. Ann Biomed Eng 39: 1935–1946. Available: http://dx.doi.org/10.1007/s10439-011-0292-7.
SponsorsThis work was supported by the New Zealand Foundation for Research, Science, and Technology, through grants NERF 139400 and NERF 9077/3608892. This publication is also based on work supported in part by Award No KUK-C1-013-04, made by King Abdullah University of Science and Technology (KAUST).
JournalAnnals of Biomedical Engineering
CollectionsPublications Acknowledging KAUST Support
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