Show simple item record

dc.contributor.authorBörjesson, Karl
dc.contributor.authorWiberg, Joanna
dc.contributor.authorEl-Sagheer, Afaf H.
dc.contributor.authorLjungdahl, Thomas
dc.contributor.authorMårtensson, Jerker
dc.contributor.authorBrown, Tom
dc.contributor.authorNordén, Bengt
dc.contributor.authorAlbinsson, Bo
dc.date.accessioned2016-02-25T13:19:51Z
dc.date.available2016-02-25T13:19:51Z
dc.date.issued2010-09
dc.identifier.citationBörjesson K, Wiberg J, El-Sagheer AH, Ljungdahl T, Mårtensson J, et al. (2010) Functionalized Nanostructures: Redox-Active Porphyrin Anchors for Supramolecular DNA Assemblies. ACS Nano 4: 5037–5046. Available: http://dx.doi.org/10.1021/nn100667b.
dc.identifier.issn1936-0851
dc.identifier.issn1936-086X
dc.identifier.pmid20809571
dc.identifier.doi10.1021/nn100667b
dc.identifier.urihttp://hdl.handle.net/10754/598387
dc.description.abstractWe have synthesized and studied a supramolecular system comprising a 39-mer DNA with porphyrin-modified thymidine nucleosides anchored to the surface of large unilamellar vesicles (liposomes). Liposome porphyrin binding characteristics, such as orientation, strength, homogeneity, and binding site size, was determined, suggesting that the porphyrin is well suited as a photophysical and redox-active lipid anchor, in comparison to the inert cholesterol anchor commonly used today. Furthermore, the binding characteristics and hybridization capabilities were studied as a function of anchor size and number of anchoring points, properties that are of importance for our future plans to use the addressability of these redox-active nodes in larger DNA-based nanoconstructs. Electron transfer from photoexcited porphyrin to a lipophilic benzoquinone residing in the lipid membrane was characterized by steady-state and time-resolved fluorescence and verified by femtosecond transient absorption. © 2010 American Chemical Society.
dc.description.sponsorshipThis research is founded by King Abdullah University of Science and Technology, The Swedish Research Council (VR), The Swedish Energy Agency, and Knut and Alice Wallenbergs Foundation.
dc.publisherAmerican Chemical Society (ACS)
dc.subjectDNA
dc.subjectelectron transfer
dc.subjectmembrane
dc.subjectnanotechnology
dc.subjectporphyrin
dc.subjectsupramolecular
dc.titleFunctionalized Nanostructures: Redox-Active Porphyrin Anchors for Supramolecular DNA Assemblies
dc.typeArticle
dc.identifier.journalACS Nano
dc.contributor.institutionChalmers University of Technology, Göteborg, Sweden
dc.contributor.institutionUniversity of Southampton, Southampton, United Kingdom
dc.contributor.institutionSuez Canal University, Ismalia, Egypt
dc.contributor.institutionGoteborgs Universitet, Goteborg, Sweden
dc.date.published-online2010-09
dc.date.published-print2010-09-28


This item appears in the following Collection(s)

Show simple item record