Type
ArticleKAUST Grant Number
KUK-I1-012-43Date
2011-09-17Online Publication Date
2011-09-17Print Publication Date
2011Permanent link to this record
http://hdl.handle.net/10754/598253
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This work presents the results of the assessment of the intramolecular residue-residue contact predictions submitted to CASP9. The methodology for the assessment does not differ from that used in previous CASPs, with two basic evaluation measures being the precision in recognizing contacts and the difference between the distribution of distances in the subset of predicted contact pairs versus all pairs of residues in the structure. The emphasis is placed on the prediction of long-range contacts (i.e., contacts between residues separated by at least 24 residues along sequence) in target proteins that cannot be easily modeled by homology. Although there is considerable activity in the field, the current analysis reports no discernable progress since CASP8.Citation
Monastyrskyy B, Fidelis K, Tramontano A, Kryshtafovych A (2011) Evaluation of residue-residue contact predictions in CASP9. Proteins: Structure, Function, and Bioinformatics 79: 119–125. Available: http://dx.doi.org/10.1002/prot.23160.Sponsors
Grant sponsor: National Library of Medicine (NIH/NLM); Grant number: LM007085; Grant sponsor: KAUST Award; Grant number: KUK-I1-012-43.Publisher
WileyPubMed ID
21928322PubMed Central ID
PMC3226919ae974a485f413a2113503eed53cd6c53
10.1002/prot.23160
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