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dc.contributor.authorReymer, Anna
dc.contributor.authorNordén, Bengt
dc.date.accessioned2016-02-25T13:13:53Z
dc.date.available2016-02-25T13:13:53Z
dc.date.issued2012
dc.identifier.citationReymer A, Nordén B (2012) Enantiospecific kinking of DNA by a partially intercalating metal complex. Chem Commun 48: 4941. Available: http://dx.doi.org/10.1039/c2cc31176c.
dc.identifier.issn1359-7345
dc.identifier.issn1364-548X
dc.identifier.pmid22476247
dc.identifier.doi10.1039/c2cc31176c
dc.identifier.urihttp://hdl.handle.net/10754/598163
dc.description.abstractOpposite enantiomers of [Ru(phenanthroline) 3] 2+ affect the persistence length of DNA differently, a long speculated effect of helix kinking. Our molecular dynamics simulations confirm a substantial change of duplex secondary structure produced by wedge-intercalation of one but not the other enantiomer. This effect is exploited by several classes of DNA operative proteins. © The Royal Society of Chemistry 2012.
dc.description.sponsorshipThis work was supported by King Abdullah University of Science and Technology, Grant [KUK-11-008-23] awarded to B.N.
dc.publisherRoyal Society of Chemistry (RSC)
dc.titleEnantiospecific kinking of DNA by a partially intercalating metal complex
dc.typeArticle
dc.identifier.journalChemical Communications
dc.contributor.institutionChalmers University of Technology, Göteborg, Sweden
kaust.grant.numberKUK-11-008-23


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