Type
ArticleDate
2012-06-13Online Publication Date
2012-06-13Print Publication Date
2012-07-06Permanent link to this record
http://hdl.handle.net/10754/598098
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A method for efficient and aldehyde-selective Wacker oxidation of aryl-substituted olefins using PdCl 2(MeCN) 2, 1,4-benzoquinone, and t-BuOH in air is described. Up to a 96% yield of aldehyde can be obtained, and up to 99% selectivity can be achieved with styrene-related substrates. © 2012 American Chemical Society.Citation
Teo P, Wickens ZK, Dong G, Grubbs RH (2012) Efficient and Highly Aldehyde Selective Wacker Oxidation. Organic Letters 14: 3237–3239. Available: http://dx.doi.org/10.1021/ol301240g.Sponsors
We gratefully acknowledge financial support from King Abdullah University of Science and Technology Centre in Development, King Fahd University of Petroleum and Minerals, and the NSF. G.D. thanks the Camille and Henry Dreyfus Foundation for a postdoctoral fellowship.Publisher
American Chemical Society (ACS)Journal
Organic LettersPubMed ID
22694293ae974a485f413a2113503eed53cd6c53
10.1021/ol301240g
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