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dc.contributor.authorQian, Pei-Yuan
dc.contributor.authorXu, Sharon Ying
dc.date.accessioned2016-02-25T12:42:38Z
dc.date.available2016-02-25T12:42:38Z
dc.date.issued2012
dc.identifier.citationQian P-Y, Xu SY (2012) Antifouling Activity of Marine Natural Products. Handbook of Marine Natural Products: 749–821. Available: http://dx.doi.org/10.1007/978-90-481-3834-0_14.
dc.identifier.doi10.1007/978-90-481-3834-0_14
dc.identifier.urihttp://hdl.handle.net/10754/597589
dc.description.abstractWith the global ban of application of organotin-based marine coatings by International Maritime Organization in 2008, there is a practical and urgent need of identifying environmentally friendly low-toxic and nontoxic antifouling compounds for marine industries. Marine natural products have been considered as one of the most promising sources of antifouling compounds in recent years. In antifouling compound screening processes, bioassay systems often play most critical/vital roles in screening efforts. To meet various needs, a variety of bioassay systems have been developed and/or adopted in both research and commercial laboratories. In this chapter, we provide a brief outline of common bioassay procedures for both antimicrofouling and antimacrofouling assays, which can serve as a general guideline for setting up bioassay systems in laboratories engaged in antifouling compound screening. Some bioassay procedures currently practiced in various laboratories are not included in this book chapter for various reasons. Individual laboratories should modify bioassay protocols based on their research interests or needs. Nevertheless, we highly recommend the research laboratories to adapt high-throughput assays as much as possible for preliminary screening assays, followed by more complex bioassay processes using multiple target species. We argue strongly for studies in mode-of-action of antifouling compounds against settling propagules, which shall lead to discovery of molecular biomarkers (genes, proteins, receptors, or receptor system) and will allow us to design more targeted bioassay systems.
dc.description.sponsorshipKAUST Global Collaborative Program
dc.publisherSpringer Science + Business Media
dc.titleAntifouling Activity of Marine Natural Products
dc.typeBook Chapter
dc.identifier.journalHandbook of Marine Natural Products
dc.contributor.institutionKAUST Global Collaborative Program, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China


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