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dc.contributor.authorTadross, Pamela M.
dc.contributor.authorBugga, Pradeep
dc.contributor.authorStoltz, Brian M.
dc.date.accessioned2016-02-25T12:32:11Z
dc.date.available2016-02-25T12:32:11Z
dc.date.issued2011
dc.identifier.citationTadross PM, Bugga P, Stoltz BM (2011) A rapid and convergent synthesis of the integrastatin core. Org Biomol Chem 9: 5354. Available: http://dx.doi.org/10.1039/c1ob05725a.
dc.identifier.issn1477-0520
dc.identifier.issn1477-0539
dc.identifier.pmid21681334
dc.identifier.doi10.1039/c1ob05725a
dc.identifier.urihttp://hdl.handle.net/10754/597388
dc.description.abstractThe tetracyclic core of the integrastatin natural products has been prepared in a convergent and rapid manner. Our strategy relies upon a palladium(ii)-catalyzed oxidative cyclization to form the central [3.3.1]-dioxabicycle of the natural product core. Overall, the core has been completed in only 4 linear steps from known compounds. © 2011 The Royal Society of Chemistry.
dc.description.sponsorshipThis publication is based on work supported by Award No. KUS-11-006-02, made by King Abdullah University of Science and Technology (KAUST). Financial support from Caltech, the Rose Hills Foundation (undergraduate fellowship to P.B.), and the California HIV/AIDS Research Program (graduate fellowship to P.M.T.) is also gratefully acknowledged.
dc.publisherRoyal Society of Chemistry (RSC)
dc.titleA rapid and convergent synthesis of the integrastatin core
dc.typeArticle
dc.identifier.journalOrganic & Biomolecular Chemistry
dc.contributor.institutionCalifornia Institute of Technology, Pasadena, United States
kaust.grant.numberKUS-11-006-02


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