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dc.contributor.authorLe Pera, Loredana
dc.contributor.authorMarcatili, Paolo
dc.contributor.authorTramontano, Anna
dc.date.accessioned2016-02-21T08:51:08Z
dc.date.available2016-02-21T08:51:08Z
dc.date.issued2010-10-12
dc.identifier.citationLe Pera L, Marcatili P, Tramontano A (2010) PICMI: mapping point mutations on genomes. Bioinformatics 26: 2904–2905. Available: http://dx.doi.org/10.1093/bioinformatics/btq547.
dc.identifier.issn1367-4803
dc.identifier.issn1460-2059
dc.identifier.pmid20940168
dc.identifier.doi10.1093/bioinformatics/btq547
dc.identifier.urihttp://hdl.handle.net/10754/596811
dc.description.abstractMOTIVATION: Several international collaborations and local projects are producing extensive catalogues of genomic variations that are supplementing existing collections such as the OMIM catalogue. The flood of this type of data will keep increasing and, especially, it will be relevant to a wider user base, including not only molecular biologists, geneticists and bioinformaticians, but also clinical researchers. Mapping the observed variations, sometimes only described at the amino acid level, on a genome, identifying whether they affect a gene and-if so-whether they also affect different isoforms of the same gene, is a time consuming and often frustrating task. RESULTS: The PICMI server is an easy to use tool for quickly mapping one or more amino acid or nucleotide variations on a genome and its products, including alternatively spliced isoforms. AVAILABILITY: The server is available at www.biocomputing.it/picmi.
dc.description.sponsorshipKAUST (Award N. KUK-I1-012-43) and FIRB (Italbionet and Proteomica).
dc.publisherOxford University Press (OUP)
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by-nc/2.0/uk/
dc.subject.meshPoint Mutation
dc.subject.meshGenome
dc.subject.meshSoftware
dc.titlePICMI: mapping point mutations on genomes.
dc.typeArticle
dc.identifier.journalBioinformatics
dc.identifier.pmcidPMC2971578
dc.contributor.institutionUniversita degli Studi di Roma La Sapienza, Rome, Italy
dc.contributor.institutionUniversita degli Studi di Roma La Sapienza, Rome, Italy
kaust.grant.numberKUK-I1-012-43
refterms.dateFOA2018-06-13T12:07:50Z


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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.