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dc.contributor.authorWu, Jinbo
dc.contributor.authorKwok, Tsz Yan
dc.contributor.authorLi, Xiaolin
dc.contributor.authorCao, Wenbin
dc.contributor.authorWang, Yu
dc.contributor.authorHuang, Junying
dc.contributor.authorHong, Yaying
dc.contributor.authorZhang, Dongen
dc.contributor.authorWen, Weijia
dc.date.accessioned2016-02-21T08:50:56Z
dc.date.available2016-02-21T08:50:56Z
dc.date.issued2013-11-25
dc.identifier.citationWu J, Kwok TY, Li X, Cao W, Wang Y, et al. (2013) Mapping three-dimensional temperature in microfluidic chip. Scientific Reports 3. Available: http://dx.doi.org/10.1038/srep03321.
dc.identifier.issn2045-2322
dc.identifier.pmid24276475
dc.identifier.doi10.1038/srep03321
dc.identifier.urihttp://hdl.handle.net/10754/596800
dc.description.abstractThree-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.
dc.description.sponsorshipThe authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST).
dc.publisherSpringer Nature
dc.rightsThis work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/
dc.titleMapping three-dimensional temperature in microfluidic chip.
dc.typeArticle
dc.identifier.journalScientific Reports
dc.identifier.pmcidPMC3839638
dc.contributor.institutionDepartment of Physics, the Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong.
kaust.grant.numberSA-C0040/UK-C0016
refterms.dateFOA2018-06-13T12:07:21Z
dc.date.published-online2013-11-25
dc.date.published-print2013-12


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This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit
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