Show simple item record

dc.contributor.authorChailyan, Anna
dc.contributor.authorTramontano, Anna
dc.contributor.authorMarcatili, Paolo
dc.date.accessioned2016-02-21T08:49:57Z
dc.date.available2016-02-21T08:49:57Z
dc.date.issued2011-11-10
dc.identifier.citationChailyan A, Tramontano A, Marcatili P (2011) A database of immunoglobulins with integrated tools: DIGIT. Nucleic Acids Research 40: D1230–D1234. Available: http://dx.doi.org/10.1093/nar/gkr806.
dc.identifier.issn0305-1048
dc.identifier.issn1362-4962
dc.identifier.pmid22080506
dc.identifier.doi10.1093/nar/gkr806
dc.identifier.urihttp://hdl.handle.net/10754/596755
dc.description.abstractThe DIGIT (Database of ImmunoGlobulins with Integrated Tools) database (http://biocomputing.it/digit) is an integrated resource storing sequences of annotated immunoglobulin variable domains and enriched with tools for searching and analyzing them. The annotations in the database include information on the type of antigen, the respective germline sequences and on pairing information between light and heavy chains. Other annotations, such as the identification of the complementarity determining regions, assignment of their structural class and identification of mutations with respect to the germline, are computed on the fly and can also be obtained for user-submitted sequences. The system allows customized BLAST searches and automatic building of 3D models of the domains to be performed.
dc.description.sponsorshipKing Abdullah University of Science and Technology (KAUST) (Award number KUK-I1-012-43); FIRB Proteomica, Ministery of Health grant (Contract No. Onc_Ord 25/07); IIT SEED project. Funding for open access charge: King Abdullah University of Science and Technology (KAUST) (Award number KUK-I1-012-43).
dc.publisherOxford University Press (OUP)
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0
dc.subject.meshDatabases, Protein
dc.titleA database of immunoglobulins with integrated tools: DIGIT.
dc.typeArticle
dc.identifier.journalNucleic Acids Research
dc.identifier.pmcidPMC3245095
dc.contributor.institutionUniversita degli Studi di Roma La Sapienza, Rome, Italy
dc.contributor.institutionIstituto Italiano di Tecnologia, Genoa, Italy
kaust.grant.numberKUK-I1-012-43
refterms.dateFOA2018-06-13T12:03:36Z
dc.date.published-online2011-11-10
dc.date.published-print2012-01-01


Files in this item

Thumbnail
Name:
PMC3245095.pdf
Size:
2.146Mb
Format:
PDF
Description:
Main article

This item appears in the following Collection(s)

Show simple item record

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.