3USS: a web server for detecting alternative 3'UTRs from RNA-seq experiments.
Type
ArticleKAUST Grant Number
KUK-I1-012-43Date
2015-01-22Online Publication Date
2015-01-22Print Publication Date
2015-06-01Permanent link to this record
http://hdl.handle.net/10754/596754
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Protein-coding genes with multiple alternative polyadenylation sites can generate mRNA 3'UTR sequences of different lengths, thereby causing the loss or gain of regulatory elements, which can affect stability, localization and translation efficiency. 3USS is a web-server developed with the aim of giving experimentalists the possibility to automatically identify alternative 3 ': UTRs (shorter or longer with respect to a reference transcriptome), an option that is not available in standard RNA-seq data analysis procedures. The tool reports as putative novel the 3 ': UTRs not annotated in available databases. Furthermore, if data from two related samples are uploaded, common and specific alternative 3 ': UTRs are identified and reported by the server.3USS is freely available at http://www.biocomputing.it/3uss_server.Citation
Le Pera L, Mazzapioda M, Tramontano A (2015) 3USS: a web server for detecting alternative 3’UTRs from RNA-seq experiments. Bioinformatics 31: 1845–1847. Available: http://dx.doi.org/10.1093/bioinformatics/btv035.Sponsors
This project was supported by KAUST [Grant Number KUK-I1-012-43], PRIN 20108XYHJS and Epigenomics Flagship Project—EPIGEN. Funding for open access charge: KAUST.Publisher
Oxford University Press (OUP)Journal
BioinformaticsPubMed ID
25617413PubMed Central ID
PMC4443675ae974a485f413a2113503eed53cd6c53
10.1093/bioinformatics/btv035
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Publications Acknowledging KAUST Support
Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
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