Combination Comprising Parthenolide For Use In The Treatment Of Alzheimer's Disease And Other Neurodegenerative Disorders

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Type
Patent
Patent Status
Published Application
Authors
Bajic, Vladimir B. cc
Essack, Magbubah cc
Assignee
King Abdullah University of Science and Technology
KAUST Department
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Computational Bioscience Research Center (CBRC)
Applied Mathematics and Computational Science Program
Date
2015-06-18
Submitted Date
2014-11-20
Permanent link to this record
http://hdl.handle.net/10754/594860

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Abstract
The present invention generally concerns particular methods and compositions for treatment of a neurodegenerative disease, such as Alzheimer's Disease. In particular embodiments, there is a composition comprising Parthenolide and a second agent, including an inhibitor of TLR4/MD-2/CD14, nAChR agonist, Resatorvid, Curcumin, Tilorone or a Tilorone analog, or a combination thereof.
Application Number
US 20150164858 A1
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Patents; Applied Mathematics and Computational Science Program; Computational Bioscience Research Center (CBRC); Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division