N-Heterocyclic-Carbene-Catalysed Diastereoselective Vinylogous Mukaiyama/Michael Reaction of 2-(Trimethylsilyloxy)furan and Enones
Type
ArticleKAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionChemical Science Program
Homogeneous Catalysis Laboratory (HCL)
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2015-10-15Online Publication Date
2015-10-15Print Publication Date
2015-12Permanent link to this record
http://hdl.handle.net/10754/594176
Metadata
Show full item recordAbstract
N-heterocyclic carbenes have been utilised as highly efficient nucleophilic organocatalysts to mediate vinylogous Mukaiyama/Michael reactions of 2-(trimethylsilyloxy)furan with enones to afford γ-substituted butenolides in 44-99% yield with 3:1-32:1 diastereoselectivity. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Citation
Wang Y, Du G-F, Xing F, Huang K-W, Dai B, et al. (2015) N-Heterocyclic-Carbene-Catalysed Diastereoselective Vinylogous Mukaiyama/Michael Reaction of 2-(Trimethylsilyloxy)furan and Enones. Asian J Org Chem 4: 1362–1365. Available: http://dx.doi.org/10.1002/ajoc.201500348.Sponsors
Shihezi University[2012ZRKXJQ06]National Natural Science Foundation of China[21262027, 21428302]
Publisher
Wileyae974a485f413a2113503eed53cd6c53
10.1002/ajoc.201500348