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dc.contributor.authorRaghavan, Maanasa
dc.contributor.authorSteinrücken, Matthias
dc.contributor.authorHarris, Kelley
dc.contributor.authorSchiffels, Stephan
dc.contributor.authorRasmussen, Simon
dc.contributor.authorDeGiorgio, Michael
dc.contributor.authorAlbrechtsen, Anders
dc.contributor.authorValdiosera, Cristina
dc.contributor.authorÁvila-Arcos, María C.
dc.contributor.authorMalaspinas, Anna Sapfo
dc.contributor.authorEriksson, Anders
dc.contributor.authorMoltke, Ida
dc.contributor.authorMetspalu, Mait
dc.contributor.authorHomburger, Julian R.
dc.contributor.authorWall, Jeff
dc.contributor.authorCornejo, Omar E.
dc.contributor.authorMoreno-Mayar, J. Víctor
dc.contributor.authorKorneliussen, Thorfinn S.
dc.contributor.authorPierre, Tracey
dc.contributor.authorRasmussen, Morten
dc.contributor.authorCampos, Paula F.
dc.contributor.authorDe Barros Damgaard, Peter
dc.contributor.authorAllentoft, Morten E.
dc.contributor.authorLindo, John
dc.contributor.authorMetspalu, Ene
dc.contributor.authorRodríguez-Varela, Ricardo
dc.contributor.authorMansilla, Josefina
dc.contributor.authorHenrickson, Celeste
dc.contributor.authorSeguin-Orlando, Andaine
dc.contributor.authorMalmstöm, Helena
dc.contributor.authorStafford, Thomas
dc.contributor.authorShringarpure, Suyash S.
dc.contributor.authorMoreno-Estrada, Andrés
dc.contributor.authorKarmin, Monika
dc.contributor.authorTambets, Kristiina
dc.contributor.authorBergström, Anders
dc.contributor.authorXue, Yali
dc.contributor.authorWarmuth, Vera
dc.contributor.authorFriend, Andrew D.
dc.contributor.authorSingarayer, Joy
dc.contributor.authorValdes, Paul
dc.contributor.authorBalloux, Francois
dc.contributor.authorLeboreiro, Ilán
dc.contributor.authorVera, Jose Luis
dc.contributor.authorRangel-Villalobos, Hector
dc.contributor.authorPettener, Davide
dc.contributor.authorLuiselli, Donata
dc.contributor.authorDavis, Loren G.
dc.contributor.authorHeyer, Evelyne
dc.contributor.authorZollikofer, Christoph P E
dc.contributor.authorPonce De León, Marcia S.
dc.contributor.authorSmith, Colin I.
dc.contributor.authorGrimes, Vaughan
dc.contributor.authorPike, Kelly Anne
dc.contributor.authorDeal, Michael
dc.contributor.authorFuller, Benjamin T.
dc.contributor.authorArriaza, Bernardo
dc.contributor.authorStanden, Vivien
dc.contributor.authorLuz, Maria F.
dc.contributor.authorRicaut, Francois
dc.contributor.authorGuidon, Niede
dc.contributor.authorOsipova, Ludmila
dc.contributor.authorVoevoda, Mikhail I.
dc.contributor.authorPosukh, Olga L.
dc.contributor.authorBalanovsky, Oleg
dc.contributor.authorLavryashina, Maria
dc.contributor.authorBogunov, Yuri
dc.contributor.authorKhusnutdinova, Elza
dc.contributor.authorGubina, Marina
dc.contributor.authorBalanovska, Elena
dc.contributor.authorFedorova, Sardana
dc.contributor.authorLitvinov, Sergey
dc.contributor.authorMalyarchuk, Boris
dc.contributor.authorDerenko, Miroslava
dc.contributor.authorMosher, M. J.
dc.contributor.authorArcher, David
dc.contributor.authorCybulski, Jerome
dc.date.accessioned2016-01-19T13:22:17Z
dc.date.available2016-01-19T13:22:17Z
dc.date.issued2015-07-21
dc.identifier.citationRaghavan M, Steinrucken M, Harris K, Schiffels S, Rasmussen S, et al. (2015) Genomic evidence for the Pleistocene and recent population history of Native Americans. Science 349: aab3884–aab3884. Available: http://dx.doi.org/10.1126/science.aab3884.
dc.identifier.issn0036-8075
dc.identifier.issn1095-9203
dc.identifier.pmid26198033
dc.identifier.doi10.1126/science.aab3884
dc.identifier.urihttp://hdl.handle.net/10754/594129
dc.description.abstractHow and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model. © 2015, American Association for the Advancement of Science. All rights reserved.
dc.description.sponsorship098051, European Research Council; European Research Council; 13-06-00670, RFBR, European Research Council; 14-0400725, RFBR, European Research Council; 14-06-00384, RFBR, European Research Council; 261213, ERC, European Research Council; 2R01HG003229-09, NIH, European Research Council; BB/H005854/1, BBSRC, European Research Council; BCS-1025139, NSF, European Research Council; FT0992258, ARC, European Research Council; CONACYT, European Research Council; ERC, European Research Council; DMS-1201234, NSF, European Research Council; ERC-2011-AdG 295733, ERC, European Research Council; R01-AI17892, NIH, European Research Council; R01-GM094402, NIH, European Research Council
dc.publisherAmerican Association for the Advancement of Science (AAAS)
dc.titleGenomic evidence for the Pleistocene and recent population history of Native Americans
dc.typeArticle
dc.contributor.departmentIntegrative Systems Biology Lab
dc.identifier.journalScience
dc.contributor.institutionCentre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, Denmark
dc.contributor.institutionComputer Science Division, University of California, Berkeley, Berkeley, CA, United States
dc.contributor.institutionDepartment of Statistics, University of California, Berkeley, Berkeley, CA, United States
dc.contributor.institutionDepartment of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, United States
dc.contributor.institutionDepartment of Mathematics, University of California, Berkeley, Berkeley, CA, United States
dc.contributor.institutionWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
dc.contributor.institutionCenter for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet, Building 208, Kongens Lyngby, Denmark
dc.contributor.institutionDepartmentof Biology and Statistics, Pennsylvania State University, 502 Wartik Laboratory, University Park, PA, United States
dc.contributor.institutionBioinformatics Centre, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, Copenhagen, Denmark
dc.contributor.institutionDepartment of Archaeology and History, La Trobe University, Melbourne, VIC, Australia
dc.contributor.institutionDepartment of Genetics, School of Medicine, Stanford University, 300 Pasteur Drive, Lane Building, Room L331, Stanford, CA, United States
dc.contributor.institutionDepartment of Zoology, University of Cambridge, Downing Street, Cambridge, United Kingdom
dc.contributor.institutionEstonian Biocentre, Evolutionary Biology Group, Tartu, Estonia
dc.contributor.institutionDepartment of Evolutionary Biology, University of Tartu, Tartu, Estonia
dc.contributor.institutionInstitute for Human Genetics, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA, United States
dc.contributor.institutionSchool of Biological Sciences, Washington State University, Post Office Box 644236, Heald 429, Pullman, WA, United States
dc.contributor.institutionCentro de Investigación en Ciencias del Mar y Limnología/Centro Interdisciplinar de Investigação Marinha e Ambiental, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Rua dos Bragas 289, Porto, Portugal
dc.contributor.institutionDepartment of Anthropology, University of Illinois at Urbana-Champaign, 607 S. Mathews Avenue, Urbana, IL, United States
dc.contributor.institutionCentro Mixto, Universidad Complutense de Madrid, Instituto de Salud Carlos III de Evolución y Comportamiento Humano, Madrid, Spain
dc.contributor.institutionInstituto Nacional de Antropología e Historia, Moneda 13, Centro, Cuauhtémoc, Mexico City, Mexico
dc.contributor.institutionUniversity of Utah, Department of Anthropology, 270 S 1400 E, Salt Lake City, UT, United States
dc.contributor.institutionDepartment of Evolutionary Biology and Science for Life Laboratory, Uppsala University, Norbyvägen 18D, Uppsala, Sweden
dc.contributor.institutionAcceleration Mass Spectrometry 14C Dating Centre, Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, Aarhus, Denmark
dc.contributor.institutionLaboratorio Nacional de Genómica para la Biodiversidad (LANGEBIO), Centro de Investigación y de Estudios Avanzados, Irapuato, Guanajuato, Mexico
dc.contributor.institutionGenetics Institute, University College London, Gower Street, London, United Kingdom
dc.contributor.institutionEvolutionsbiologiskt Centrum, Norbyvägen 18D, Uppsala, Sweden
dc.contributor.institutionDepartment of Geography, University of Cambridge, Downing Place, Cambridge, United Kingdom
dc.contributor.institutionCentre for Past Climate Change, Department of Meteorology, University of Reading, Earley Gate, Post Office Box 243, Reading, United Kingdom
dc.contributor.institutionSchool of Geographical Sciences, University Road, Clifton, Bristol, United Kingdom
dc.contributor.institutionEscuela Nacional de Antropología e Historia, Periférico Sur y Zapote s/n Colonia Isidro Fabela, Tlalpan, Isidro Fabela, Mexico City, Mexico
dc.contributor.institutionInstituto de Investigación en Genética Molecular, Universidad de Guadalajara, Ocotlán, Mexico
dc.contributor.institutionDipartimento di Scienze Biologiche, Geologiche e Ambientali (BiGeA), Università di Bologna, Via Selmi 3, Bologna, Italy
dc.contributor.institutionDepartment of Anthropology, Oregon State University, 238 Waldo Hall, Corvallis, OR, United States
dc.contributor.institutionMuseum National d'Histoire Naturelle, CNRS, Université Paris 7 Diderot, Paris, France
dc.contributor.institutionAnthropological Institute and Museum, University of Zürich, Winterthurerstrasse 190, Zürich, Switzerland
dc.contributor.institutionDepartment of Archaeology, Memorial University, Queen's College, 210 Prince Philip Drive, St. John's, Newfoundland, Canada
dc.contributor.institutionDepartment of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, Germany
dc.contributor.institutionDepartment of Earth System Science, University of California, Irvine, Keck Carbon Cycle Accelerator Mass Spectrometry Group, B321 Croul Hall, Irvine, CA, United States
dc.contributor.institutionInstituto de Alta Investigación, Universidad de Tarapacá, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile
dc.contributor.institutionDepartamento de Antropologia, Universidad de Tarapacá, 18 de Septiembre 2222, Carsilla 6-D Arica, Chile
dc.contributor.institutionFundação Museu do Homem Americano, Centro Cultural Sérgio Motta, Campestre, Sao Raimundo Nonato, Brazil
dc.contributor.institutionLaboratoire d'Anthropologie Moléculaire et Imagérie de Synthèse UMR-5288, CNRS, Université de Toulouse, Toulouse, France
dc.contributor.institutionInstitute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, Russian Federation
dc.contributor.institutionNovosibirsk State University, 2 Pirogova Street, Novosibirsk, Russian Federation
dc.contributor.institutionInstitute of Internal Medicine, Siberian Branch of RAS, 175/1 ul. B. Bogatkova, Novosibirsk, Russian Federation
dc.contributor.institutionNovosibirsk State University, Laboratory of Molecular Epidemiology and Bioinformatics, Novosibirsk, Russian Federation
dc.contributor.institutionVavilov Institute of General Genetics, Gubkina 3, Moscow, Russian Federation
dc.contributor.institutionResearch Centre for Medical Genetics, Moskvorechie 1, Moscow, Russian Federation
dc.contributor.institutionKemerovo State University, Krasnaya 3, Kemerovo, Russian Federation
dc.contributor.institutionInstitute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Prospekt Oktyabrya 71, Ufa, Russian Federation
dc.contributor.institutionDepartment of Genetics and Fundamental Medicine, Bashkir State University, Zaki Validi 32, Ufa, Russian Federation
dc.contributor.institutionDepartment of Molecular Genetics, Yakut Scientific Centre of Complex Medical Problems, Sergelyahskoe Shosse 4, Yakutsk, Russian Federation
dc.contributor.institutionLaboratory of Molecular Biology, Institute of Natural Sciences, M. K. Ammosov North-Eastern Federal University, Yakutsk, Russian Federation
dc.contributor.institutionInstitute of Biological Problems of the North, Russian Academy of Sciences, Portovaya Street 18, Magadan, Russian Federation
dc.contributor.institutionDepartment of Anthropology, Western Washington University, Bellingham, WA, United States
dc.contributor.institutionDepartment of Anthropology, Northwest Community College, 353 Fifth Street, 65Prince RupertBC, Canada
dc.contributor.institutionCanadian Museum of History, 100 Rue Laurier, Gatineau, QC, Canada
dc.contributor.institutionUniversity of Western Ontario, London, ON, Canada
dc.contributor.institutionSimon Fraser University, Burnaby, BC, Canada
dc.contributor.institutionMetlakatla Treaty Office, Post Office Box 224, Prince Rupert, BC, Canada
dc.contributor.institutionSealaska Heritage Institute, 105 S. Seward Street, Juneau, AK, United States
dc.contributor.institutionDepartment of Structural Biology, Stanford University School of Medicine, D100 Fairchild Science Building, Stanford, CA, United States
dc.contributor.institutionDepartment of Anthropology, Washington State University, Pullman, WA, United States
dc.contributor.institutionDivision of Biological Anthropology, University of Cambridge, Henry Wellcome Building, Fitzwilliam Street, Cambridge, United Kingdom
dc.contributor.institutionDepartment of Medicine, University of Cambridge, Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, United Kingdom
dc.contributor.institutionLaboratory of Biological Anthropology, University of Kansas, 1415 Jayhawk Boulevard, 622 Fraser Hall, Lawrence, KS, United States
dc.contributor.institutionKSMolecular Anthropology Laboratory, Department of Anthropology, University of California, One Shields Avenue, Davis, United States
dc.contributor.institutionCenter for the Study of the First Americans, Texas A and M University, College Station, United States
dc.contributor.institutionDepartment of Anthropology, Texas A and M University, College Station, TX, United States
dc.contributor.institutionDepartment of Geography, Texas A and M University, College Station, TX, United States
dc.contributor.institutionSanta Barbara Museum of Natural History, 2559 Puesta del Sol, Santa Barbara, CA, United States
dc.contributor.institutionCarle R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States
dc.contributor.institutionDepartment of Anthropology, Southern Methodist University, Dallas, TX, United States
dc.contributor.institutionDepartment of Integrative Biology, University of California, 3060 Valley Life Sciences Building 3140, Berkeley, CA, United States
kaust.personEriksson, Anders


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