Genomic evidence for the Pleistocene and recent population history of Native Americans
Type
ArticleAuthors
Raghavan, MaanasaSteinrücken, Matthias
Harris, Kelley
Schiffels, Stephan
Rasmussen, Simon
DeGiorgio, Michael
Albrechtsen, Anders
Valdiosera, Cristina
Ávila-Arcos, María C.
Malaspinas, Anna Sapfo
Eriksson, Anders

Moltke, Ida
Metspalu, Mait
Homburger, Julian R.
Wall, Jeff
Cornejo, Omar E.
Moreno-Mayar, J. Víctor
Korneliussen, Thorfinn S.
Pierre, Tracey
Rasmussen, Morten
Campos, Paula F.
De Barros Damgaard, Peter
Allentoft, Morten E.
Lindo, John
Metspalu, Ene
Rodríguez-Varela, Ricardo
Mansilla, Josefina
Henrickson, Celeste
Seguin-Orlando, Andaine
Malmstöm, Helena
Stafford, Thomas
Shringarpure, Suyash S.
Moreno-Estrada, Andrés
Karmin, Monika
Tambets, Kristiina
Bergström, Anders
Xue, Yali
Warmuth, Vera
Friend, Andrew D.
Singarayer, Joy
Valdes, Paul
Balloux, Francois
Leboreiro, Ilán
Vera, Jose Luis
Rangel-Villalobos, Hector
Pettener, Davide
Luiselli, Donata
Davis, Loren G.
Heyer, Evelyne
Zollikofer, Christoph P E
Ponce De León, Marcia S.
Smith, Colin I.
Grimes, Vaughan
Pike, Kelly Anne
Deal, Michael
Fuller, Benjamin T.
Arriaza, Bernardo
Standen, Vivien
Luz, Maria F.
Ricaut, Francois
Guidon, Niede
Osipova, Ludmila
Voevoda, Mikhail I.
Posukh, Olga L.
Balanovsky, Oleg
Lavryashina, Maria
Bogunov, Yuri
Khusnutdinova, Elza
Gubina, Marina
Balanovska, Elena
Fedorova, Sardana
Litvinov, Sergey
Malyarchuk, Boris
Derenko, Miroslava
Mosher, M. J.
Archer, David
Cybulski, Jerome
KAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionIntegrative Systems Biology Lab
Date
2015-07-21Online Publication Date
2015-07-21Print Publication Date
2015-08-21Permanent link to this record
http://hdl.handle.net/10754/594129
Metadata
Show full item recordAbstract
How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model. © 2015, American Association for the Advancement of Science. All rights reserved.Citation
Raghavan M, Steinrucken M, Harris K, Schiffels S, Rasmussen S, et al. (2015) Genomic evidence for the Pleistocene and recent population history of Native Americans. Science 349: aab3884–aab3884. Available: http://dx.doi.org/10.1126/science.aab3884.Sponsors
098051, European Research Council; European Research Council; 13-06-00670, RFBR, European Research Council; 14-0400725, RFBR, European Research Council; 14-06-00384, RFBR, European Research Council; 261213, ERC, European Research Council; 2R01HG003229-09, NIH, European Research Council; BB/H005854/1, BBSRC, European Research Council; BCS-1025139, NSF, European Research Council; FT0992258, ARC, European Research Council; CONACYT, European Research Council; ERC, European Research Council; DMS-1201234, NSF, European Research Council; ERC-2011-AdG 295733, ERC, European Research Council; R01-AI17892, NIH, European Research Council; R01-GM094402, NIH, European Research CouncilJournal
SciencePubMed ID
26198033ae974a485f413a2113503eed53cd6c53
10.1126/science.aab3884
Scopus Count
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