Geometrical Patterning of Super-Hydrophobic Biosensing Transistors Enables Space and Time Resolved Analysis of Biological Mixtures
Di Fabrizio, Enzo M.
KAUST DepartmentMaterial Science and Engineering Program
Physical Science and Engineering (PSE) Division
Online Publication Date2016-01-12
Print Publication Date2016-05
Permanent link to this recordhttp://hdl.handle.net/10754/593364
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AbstractPEDOT:PSS is a conductive polymer that can be integrated into last generation Organic Electrochemical Transistor (OECT) devices for biological inspection, identification and analysis. While a variety of reports in literature demonstrated the chemical and biological sensitivity of these devices, still their ability in resolving complex mixtures remains controversial. Similar OECT devices display good time dynamics behavior but lack spatial resolution. In this work, we integrated PEDOT:PSS with patterns of super-hydrophobic pillars in which a finite number of those pillars is independently controlled for site-selective measurement of a solution. We obtained a multifunctional, hierarchical OECT device that bridges the micro- to the nano-scales for specific, combined time and space resolved analysis of the sample. Due to super-hydrophobic surface properties, the biological species in the drop are driven by convection, diffusion, and the externally applied electric field: the balance/unbalance between these forces will cause the molecules to be transported differently within its volume depending on particle size thus realizing a size-selective separation. Within this framework, the separation and identification of two different molecules, namely Cetyl Trimethyl Ammonium Bromid (CTAB) and adrenaline, in a biological mixture have been demonstrated, showing that geometrical control at the micro-nano scale impart unprecedented selectivity to the devices.
CitationGeometrical Patterning of Super-Hydrophobic Biosensing Transistors Enables Space and Time Resolved Analysis of Biological Mixtures 2016, 6:18992 Scientific Reports
- Microtexturing of the conductive PEDOT:PSS polymer for superhydrophobic organic electrochemical transistors.
- Authors: Gentile F, Coppedè N, Tarabella G, Villani M, Calestani D, Candeloro P, Iannotta S, Di Fabrizio E
- Issue date: 2014
- Electrical performance of silicon-on-insulator field-effect transistors with multiple top-gate organic layers in electrolyte solution.
- Authors: Khamaisi B, Vaknin O, Shaya O, Ashkenasy N
- Issue date: 2010 Aug 24
- Fabrication of organic electrochemical transistor arrays for biosensing.
- Authors: Zhang M, Lin P, Yang M, Yan F
- Issue date: 2013 Sep
- Selective on site separation and detection of molecules in diluted solutions with super-hydrophobic clusters of plasmonic nanoparticles.
- Authors: Gentile F, Coluccio ML, Zaccaria RP, Francardi M, Cojoc G, Perozziello G, Raimondo R, Candeloro P, Di Fabrizio E
- Issue date: 2014 Jul 21
- Controlled electrostatic gating of carbon nanotube FET devices.
- Authors: Artyukhin AB, Stadermann M, Friddle RW, Stroeve P, Bakajin O, Noy A
- Issue date: 2006 Sep