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    AuthorChang, Donald C. (1)
    Lee, Yi-Kuen (1)
    Lin, Ran (1)Journal2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) (1)KAUST Grant Number
    SA-C0040 (1)
    UK-COOI6 (1)PublisherInstitute of Electrical and Electronics Engineers (IEEE) (1)Subject
    Actin filament (1)
    Cytochalasin D (1)
    Electroendocytosis (1)
    Micro Cell Chip (1)
    View MoreType
    Conference Paper (1)
    Year (Issue Date)2012 (1)Item AvailabilityMetadata Only (1)

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    The effect of Cytochalasin D on F-Actin behavior of single-cell electroendocytosis using multi-chamber micro cell chip

    Lin, Ran; Chang, Donald C.; Lee, Yi-Kuen (2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), Institute of Electrical and Electronics Engineers (IEEE), 2012-03) [Conference Paper]
    Electroendocytosis (EED) is a pulsed-electric-field (PEF) induced endocytosis, facilitating cells uptake molecules through nanometer-sized EED vesicles. We herein investigate the effect of a chemical inhibitor, Cytochalasin D (CD) on the actin-filaments (F-Actin) behavior of single-cell EED. The CD concentration (C CD) can control the depolymerization of F-actin. A multi-chamber micro cell chip was fabricated to study the EED under different conditions. Large-scale single-cell data demonstrated EED highly depends on both electric field and C CD. © 2012 IEEE.
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