Arabidopsis Yak1 protein (AtYak1) is a dual specificity protein kinase
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KAUST Department
Biological and Environmental Science and Engineering (BESE) DivisionCenter for Desert Agriculture
Plant Science
Plant Stress Genomics Research Lab
Date
2015-10-09Online Publication Date
2015-10-09Print Publication Date
2015-10-24Permanent link to this record
http://hdl.handle.net/10754/579844Metadata
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Yak1 is a member of dual-specificity Tyr phosphorylation-regulated kinases (DYRKs) that are evolutionarily conserved. The downstream targets of Yak1 and their functions are largely unknown. Here, a homologous protein AtYAK1 was identified in Arabidopsis thaliana and the phosphoprotein profiles of the wild type and an atyak1 mutant were compared on two-dimensional gel following Pro-Q Diamond phosphoprotein gel staining. Annexin1, Annexin2 and RBD were phosphorylated at serine/ threonine residues by the AtYak1 kinase. Annexin1, Annexin2 and Annexin4 were also phosphorylated at tyrosine residues. Our study demonstrated that AtYak1 is a dual specificity protein kinase in Arabidopsis that may regulate the phosphorylation status of the annexin family proteins.Citation
Arabidopsis Yak1 protein (AtYak1) is a dual specificity protein kinase 2015 FEBS LettersPublisher
WileyJournal
FEBS LettersPubMed ID
26452715Additional Links
http://linkinghub.elsevier.com/retrieve/pii/S0014579315008741Scopus Count
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