Detection of antibiotic resistance in probiotics of dietary supplements
AuthorsWong, Aloysius Tze
Ngu, Davey Yueh Saint
Dan, Lydia Annabel
Ooi, Amanda Siok Lee
Lim, Renee Lay Hong
MetadataShow full item record
AbstractBackground Probiotics are live microorganisms that confer nutrition- and health-promoting benefits if consumed in adequate amounts. Concomitant with the demand for natural approaches to maintaining health is an increase in inclusion of probiotics in food and health products. Since probiotic bacteria act as reservoir for antibiotic resistant determinants, the transfer of these genes to pathogens sharing the same intestinal habitat is thus conceivable considering the fact that dietary supplements contain high amounts of often heterogeneous populations of probiotics. Such events can confer pathogens protection against commonly-used drugs. Despite numerous reports of antibiotic resistant probiotics in food and biological sources, the antibiogram of probiotics from dietary supplements remained elusive. Findings Here, we screened five commercially available dietary supplements for resistance towards antibiotics of different classes. Probiotics of all batches of products were resistant towards vancomycin while batch-dependent resistance towards streptomycin, aztreonam, gentamycin and/or ciprofloxacin antibiotics was detected for probiotics of brands Bi and Bn, Bg, and L. Isolates of brand Cn was also resistant towards gentamycin, streptomycin and ciprofloxacin antibiotics. Additionally, we also report a discrepancy between the enumerated viable bacteria amounts and the claims of the manufacturers. Conclusions This short report has highlighted the present of antibiotic resistance in probiotic bacteria from dietary supplements and therefore serves as a platform for further screenings and for in-depth characterization of the resistant determinants and the molecular machinery that confers the resistance.
CitationDetection of antibiotic resistance in probiotics of dietary supplements 2015, 14 (1) Nutrition Journal
Is Supplemented ByWong, A., Ngu, D., Dan, L., Ooi, A., & Lim, R. (2015). Detection of antibiotic resistance in probiotics of dietary supplements. Figshare. https://doi.org/10.6084/m9.figshare.c.3697372
- Assessing the Risk of Probiotic Dietary Supplements in the Context of Antibiotic Resistance.
- Authors: Zheng M, Zhang R, Tian X, Zhou X, Pan X, Wong A
- Issue date: 2017
- Characterization of Antibiotic Resistance Genes from Lactobacillus Isolated from Traditional Dairy Products.
- Authors: Guo H, Pan L, Li L, Lu J, Kwok L, Menghe B, Zhang H, Zhang W
- Issue date: 2017 Mar
- Identification and antibiotic susceptibility of bacterial isolates from probiotic products.
- Authors: Temmerman R, Pot B, Huys G, Swings J
- Issue date: 2003 Feb 25
- Identification and antibiotic susceptibility of bacterial isolates from probiotic products available in Italy.
- Authors: Milazzo I, Speciale A, Musumeci R, Fazio D, Blandino G
- Issue date: 2006 Oct
- Identification of Lactobacillus ruminus SPM0211 isolated from healthy Koreans and its antimicrobial activity against some pathogens.
- Authors: Yun JH, Yim DS, Kang JY, Kang BY, Shin EA, Chung MJ, Kim SD, Baek DH, Kim K, Ha NJ
- Issue date: 2005 Jun