Stone-dwelling actinobacteria Blastococcus saxobsidens, Modestobacter marinus and Geodermatophilus obscurus proteogenomes
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Type
ArticleAuthors
Sghaier, HaïthamHezbri, Karima

Ghodhbane-Gtari, Faten
Pujic, Petar
Sen, Arnab
Daffonchio, Daniele

Boudabous, Abdellatif
Tisa, Louis S
Klenk, Hans-Peter
Armengaud, Jean
Normand, Philippe
Gtari, Maher

KAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionBioscience Program
Date
2015-06-30Online Publication Date
2015-06-30Print Publication Date
2016-01Permanent link to this record
http://hdl.handle.net/10754/577333
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Show full item recordAbstract
The Geodermatophilaceae are unique model systems to study the ability to thrive on or within stones and their proteogenomes (referring to the whole protein arsenal encoded by the genome) could provide important insight into their adaptation mechanisms. Here we report the detailed comparative genome analysis of Blastococcus saxobsidens (Bs), Modestobacter marinus (Mm) and Geodermatophilus obscurus (Go) isolated respectively from the interior and the surface of calcarenite stones and from desert sandy soils. The genome-scale analysis of Bs, Mm and Go illustrates how adaptation to these niches can be achieved through various strategies including ‘molecular tinkering/opportunism’ as shown by the high proportion of lost, duplicated or horizontally transferred genes and ORFans. Using high-throughput discovery proteomics, the three proteomes under unstressed conditions were analyzed, highlighting the most abundant biomarkers and the main protein factors. Proteomic data corroborated previously demonstrated stone-related ecological distribution. For instance, these data showed starvation-inducible, biofilm-related and DNA-protection proteins as signatures of the microbes associated with the interior, surface and outside of stones, respectively.Citation
Stone-dwelling actinobacteria Blastococcus saxobsidens, Modestobacter marinus and Geodermatophilus obscurus proteogenomes 2015 The ISME JournalPublisher
Springer NatureJournal
The ISME JournalAdditional Links
http://www.nature.com/doifinder/10.1038/ismej.2015.108ae974a485f413a2113503eed53cd6c53
10.1038/ismej.2015.108