• In Situ Spectroscopic Ellipsometry in the Field of Industrial Membranes

      Ogieglo, Wojciech (Springer International Publishing, 2018-05-06)
      Industrial membranes are playing an ever increasing role in the ongoing and necessary transition of our society towards more sustainable growth and development. Already today membranes offer more energy efficient alternatives to the traditional often very energy intensive industrial separation processes such as (cryogenic) distillation or crystallization. For many years reverse osmosis membranes have offered a viable method for the production of potable water via desalination processes and their significance continuously increases. Recently, membrane technology has been demonstrated to play a significant role in potential methods to generate or store energy on an industrial scale. For molecular separations often the key for an efficient membrane operation often lies in the application of an (ultra-) thin organic polymer, inorganic or hybrid selective layer whose interaction with the separated mixture defines the membrane performance. Ellipsometry has started gaining increasing attention in this area due to its large potential to conduct in-situ, non-destructive and very precise analysis of the film-fluid interactions. In this chapter, we aim to review the important recent developments in the application of ellipsometry in industrial membrane-related studies. We briefly introduce the basics of membrane science and discuss the used experimental setups and optical models. Further we focus on fundamental studies of sorption, transport and penetrant-induced phenomena in thin films exposed to organic solvents or high pressure gases. The application of in-situ ellipsometry is discussed for studies of new, promising membrane materials and the use of the technique for emerging direct studies of operating membranes is highlighted.
    • Impact of MCT1 Haploinsufficiency on the Mouse Retina

      Peachey, Neal S.; Yu, Minzhong; Han, John Y. S.; Lengacher, Sylvain; Magistretti, Pierre J.; Pellerin, Luc; Philp, Nancy J. (Springer International Publishing, 2018-05-02)
      The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1+/− heterozygotes, which express half of the normal complement of MCT1. The MCT1+/− retina developed normally and retained normal function, indicating that MCT1 is expressed at sufficient levels to support outer retinal metabolism.
    • Adsorption desalination—Principles, process design, and its hybrids for future sustainable desalination

      Shahzad, Muhammad Wakil; Burhan, Muhammad; Ang, Li; Ng, Kim Choon (Elsevier, 2018-05-03)
      The energy, water, and environment nexus is a crucial factor when considering the future development of desalination plants or industry in water-stressed economies. The new generation of desalination processes or plants has to meet the stringent environment discharge requirements and yet the industry remains highly energy efficient and sustainable when producing good potable water. Water sources, either brackish or seawater, have become more contaminated as feed while the demand for desalination capacities increases around the world. One immediate solution for energy efficiency improvement comes from the hybridization of the proven desalination processes to the newer processes of desalination: For example, the integration of the available heat-driven to adsorption desalination (AD) cycles where significant thermodynamic synergy can be attained when cycles are combined. For these hybrid cycles, a quantum improvement in energy efficiency as well as an increase in water production can be expected. The advent of MED with AD cycles, or simply called the MED-AD cycles, is one such example where seawater desalination can be pursued and operated in cogeneration with the electricity production plants: The hybrid desalination cycles utilize only the low exergy bled-stream at low temperatures, complemented with waste exhaust or renewable solar thermal heat at temperatures between 60°C and 80°C. In this chapter, the authors have reported their pioneered research on aspects of AD and related hybrid MED-AD cycles, both at theoretical models and experimental pilots. Using the cogeneration of electricity and desalination concepts, the authors examine the cost apportionment of fuel cost by the quality or exergy of the working steam for such cogeneration configurations.
    • Hepatitis C Virus: Virology and Genotypes

      Abdelaziz, Ahmed (Elsevier, 2017-12-01)
      Hepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. HCV genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.
    • Alkane Metathesis

      Basset, Jean-Marie; Callens, Emmanuel; Riache, Nassima (Wiley-VCH Verlag GmbH & Co. KGaA, 2015-03-29)
      Catalytic activation of alkanes which directly transforms light alkanes into higher homologs is a major area in organometallic chemistry and petrochemical chemistry. This transformation is a chemical challenge considering the inertness of the sp3 carbon-hydrogen bond. It is generally accepted that this catalytic process involves the formation of olefins. This reaction is defined as alkane metathesis. To date, two catalytic systems of alkane metathesis exist: (i) a single catalytic system prepared by surface organometallic chemistry, acting as multifunctional-supported catalyst which transforms any alkanes into a mixture of their lower and higher homologs and (ii) the other catalytic systems employing a tandem strategy with two different metals, one metal for alkane (de)hydrogenation and another for olefin metathesis in which the activity of these catalysts is essentially driven by the performance of the (de)hydrogenation steps. In this book chapter, we would focus on the evolution of these two classes of catalysts by looking at their specific reactivity of the catalysts towards alkanes, comparing their performances and studying the mechanism.
    • TDZ-Induced Plant Regeneration in Jatropha curcas: A Promising Biofuel Plant

      Kumar, Nitish; Bhatt, Vacha D.; Mastan, Shaik G.; Reddy, Muppala P. (Springer Singapore, 2018-03-23)
      In recent years, Jatropha curcas has pronounced attention due to its capacity of production of biodiesel. Uniform large-scale propagation of J. curcas is one of the significant keys that will eventually decide victory. Direct regeneration is one of the methods which help in the production of uniform and homogenous plant, and TDZ plays an important role in the production of plantlets by direct organogenesis in several number of plant species including J. curcas. Measuring the economical importance of J. curcas and the role of TDZ in shoot regeneration, the present book chapter briefly reviews the impact of TDZ on shoot bud induction from various explants of J. curcas.
    • Simple Finite Sums

      Alabdulmohsin, Ibrahim M. (Springer International Publishing, 2018-03-07)
      We will begin our treatment of summability calculus by analyzing what will be referred to, throughout this book, as simple finite sums. Even though the results of this chapter are particular cases of the more general results presented in later chapters, they are important to start with for a few reasons. First, this chapter serves as an excellent introduction to what summability calculus can markedly accomplish. Second, simple finite sums are encountered more often and, hence, they deserve special treatment. Third, the results presented in this chapter for simple finite sums will, themselves, be used as building blocks for deriving the most general results in subsequent chapters. Among others, we establish that fractional finite sums are well-defined mathematical objects and show how various identities related to the Euler constant as well as the Riemann zeta function can actually be derived in an elementary manner using fractional finite sums.
    • Oscillating Finite Sums

      Alabdulmohsin, Ibrahim M. (Springer International Publishing, 2018-03-07)
      In this chapter, we use the theory of summability of divergent series, presented earlier in Chap. 4, to derive the analogs of the Euler-Maclaurin summation formula for oscillating sums. These formulas will, in turn, be used to perform many remarkable deeds with ease. For instance, they can be used to derive analytic expressions for summable divergent series, obtain asymptotic expressions of oscillating series, and even accelerate the convergence of series by several orders of magnitude. Moreover, we will prove the notable fact that, as far as the foundational rules of summability calculus are concerned, summable divergent series behave exactly as if they were convergent.
    • Composite Finite Sums

      Alabdulmohsin, Ibrahim M. (Springer International Publishing, 2018-03-07)
      In this chapter, we extend the previous results of Chap. 2 to the more general case of composite finite sums. We describe what composite finite sums are and how their analysis can be reduced to the analysis of simple finite sums using the chain rule. We apply these techniques, next, on numerical integration and on some identities of Ramanujan.
    • Analytic Summability Theory

      Alabdulmohsin, Ibrahim M. (Springer International Publishing, 2018-03-07)
      The theory of summability of divergent series is a major branch of mathematical analysis that has found important applications in engineering and science. It addresses methods of assigning natural values to divergent sums, whose prototypical examples include the Abel summation method, the Cesaro means, and the Borel summability method. As will be established in subsequent chapters, the theory of summability of divergent series is intimately connected to the theory of fractional finite sums. In this chapter, we introduce a generalized definition of series as well as a new summability method for computing the value of series according to such a definition. We show that the proposed summability method is both regular and linear, and that it arises quite naturally in the study of local polynomial approximations of analytic functions. The materials presented in this chapter will be foundational to all subsequent chapters.
    • Development of Falling Film Heat Transfer Coefficient for Industrial Chemical Processes Evaporator Design

      Shahzad, Muhammad Wakil; Burhan, Muhammad; Ng, Kim Choon (InTech, 2018-03-07)
      In falling film evaporators, the overall heat transfer coefficient is controlled by film thickness, velocity, liquid properties and the temperature differential across the film layer. This chapter presents the heat transfer behaviour for evaporative film boiling on horizontal tubes, but working at low pressures of 0.93–3.60 kPa as well as seawater salinity of 15,000–90,000 mg/l or ppm. Owing to a dearth of literature on film-boiling at these conditions, the chapter is motivated by the importance of evaporative film-boiling in the process industries. It is observed that in addition to the above-mentioned parameters, evaporative heat transfer of seawater is affected by the emergence of micro-bubbles within the thin film layer, particularly when the liquid saturation temperatures drop below 25°C (3.1 kPa). Such micro-bubbles are generated near to the tube wall surfaces, and they enhanced the heat transfer by two or more folds when compared with the predictions of conventional evaporative film-boiling. The appearance of micro-bubbles is attributed to the rapid increase in the specific volume of vapour, i.e. dv/dT, at low saturation temperature conditions. A new correlation is thus proposed in this chapter and it shows good agreement to the measured data with an experimental uncertainty less than ±8%.
    • PCNA Loading by RFC, Mechanism of

      Oke, Muse; Zaher, Manal S.; Hamdan, Samir (Springer New York, 2018-01-29)
      Replicative polymerases achieve highly processive DNA synthesis by binding to a clamp-like processivity factor that is topologically linked to DNA. The eukaryotic processivity clamp, proliferating cell nuclear antigen (PCNA), exists mostly as a closed ring in solution. Replication factor C (RFC), a five-subunit ATP-dependent protein complex, mediates PCNA opening in solution (assembly stage) and closing onto the primer-template (disassembly stage). In the assembly stage, RFC binding to ATP causes conformational changes that trigger RFC to form a complex with PCNA. PCNA is then cracked open at one subunit interface, and both RFC and PCNA adopt an extended spiral structure with a chamber that selects for a primer-template DNA structure. Binding of RFC/PCNA to DNA triggers the disassembly stage by stimulating ATP hydrolysis. Subsequent conformational changes in RFC and PCNA lead to the closing of PCNA onto the primer-template and the dissociation of RFC.
    • PCNA Structure and Interactions with Partner Proteins

      Oke, Muse; Zaher, Manal S.; Hamdan, Samir (Springer New York, 2018-01-29)
      Proliferating cell nuclear antigen (PCNA) consists of three identical monomers that topologically encircle double-stranded DNA. PCNA stimulates the processivity of DNA polymerase δ and, to a less extent, the intrinsically highly processive DNA polymerase ε. It also functions as a platform that recruits and coordinates the activities of a large number of DNA processing proteins. Emerging structural and biochemical studies suggest that the nature of PCNA-partner proteins interactions is complex. A hydrophobic groove at the front side of PCNA serves as a primary docking site for the consensus PIP box motifs present in many PCNA-binding partners. Sequences that immediately flank the PIP box motif or regions that are distant from it could also interact with the hydrophobic groove and other regions of PCNA. Posttranslational modifications on the backside of PCNA could add another dimension to its interaction with partner proteins. An encounter of PCNA with different DNA structures might also be involved in coordinating its interactions. Finally, the ability of PCNA to bind up to three proteins while topologically linked to DNA suggests that it would be a versatile toolbox in many different DNA processing reactions.
    • Genome Sequences of Oryza Species

      Kumagai, Masahiko; Tanaka, Tsuyoshi; Ohyanagi, Hajime; Hsing, Yue-Ie C.; Itoh, Takeshi (Springer Singapore, 2018-02-14)
      This chapter summarizes recent data obtained from genome sequencing, annotation projects, and studies on the genome diversity of Oryza sativa and related Oryza species. O. sativa, commonly known as Asian rice, is the first monocot species whose complete genome sequence was deciphered based on physical mapping by an international collaborative effort. This genome, along with its accurate and comprehensive annotation, has become an indispensable foundation for crop genomics and breeding. With the development of innovative sequencing technologies, genomic studies of O. sativa have dramatically increased; in particular, a large number of cultivars and wild accessions have been sequenced and compared with the reference rice genome. Since de novo genome sequencing has become cost-effective, the genome of African cultivated rice, O. glaberrima, has also been determined. Comparative genomic studies have highlighted the independent domestication processes of different rice species, but it also turned out that Asian and African rice share a common gene set that has experienced similar artificial selection. An international project aimed at constructing reference genomes and examining the genome diversity of wild Oryza species is currently underway, and the genomes of some species are publicly available. This project provides a platform for investigations such as the evolution, development, polyploidization, and improvement of crops. Studies on the genomic diversity of Oryza species, including wild species, should provide new insights to solve the problem of growing food demands in the face of rapid climatic changes.
    • Chapter 1: Solar, wind and geothermal energy applications in agriculture: back to the future?

      Bundschuh, Jochen; Chen, Guangnan; Tomaszewska, Barbara; Ghaffour, NorEddine; Mushtaq, Shahbaz; Hamawand, Ihsan; Reardon-Smith, Kathryn; Maraseni, Tek; Banhazi, Thomas; Mahmoudi, Hacene; Goosen, Mattheus; Antille, Diogenes L. (CRC Press, 2017-09-13)
      The agri-food chain consumes about one third of the world’s energy production with about 12% for crop production and nearly 80% for processing, distribution, retail, preparation and cooking (Fig. 1.1) (FAO, 2011a). The agri-food chain also accounts for 80-90% of total global freshwater use (Hoff, 2011) where 70% is for irrigation alone. Additionally, on a global scale, freshwater production consumes nearly 15% of the entire energy production (IEA, 2012). It can therefore be argued that making agriculture and the agri-food supply chain independent from fossil fuel use has huge potential to contribute to global food security and climate protection not only for the next decades, but also for the coming century. Provision of secure, accessible and environmentally sustainable supplies of water, energy and food must thus be a priority.
    • Acetic Acid Bacteria as Symbionts of Insects

      Crotti, Elena; Chouaia, Bessem; Alma, Alberto; Favia, Guido; Bandi, Claudio; Bourtzis, Kostas; Daffonchio, Daniele (Springer Japan, 2016-06-14)
      Acetic acid bacteria (AAB) are being increasingly described as associating with different insect species that rely on sugar-based diets. AAB have been found in several insect orders, among them Diptera, Hemiptera, and Hymenoptera, including several vectors of plant, animal, and human diseases. AAB have been shown to associate with the epithelia of different organs of the host, they are able to move within the insect’s body and to be transmitted horizontally and vertically. Here, we review the ecology of AAB and examine their relationships with different insect models including mosquitoes, leafhoppers, and honey bees. We also discuss the potential use of AAB in symbiont-based control strategies, such as “Trojan-horse” agents, to block the transmission of vector-borne diseases.
    • Game-Theoretic Learning in Distributed Control

      Marden, Jason R.; Shamma, Jeff S. (Springer International Publishing, 2018-01-05)
      In distributed architecture control problems, there is a collection of interconnected decision-making components that seek to realize desirable collective behaviors through local interactions and by processing local information. Applications range from autonomous vehicles to energy to transportation. One approach to control of such distributed architectures is to view the components as players in a game. In this approach, two design considerations are the components’ incentives and the rules that dictate how components react to the decisions of other components. In game-theoretic language, the incentives are defined through utility functions, and the reaction rules are online learning dynamics. This chapter presents an overview of this approach, covering basic concepts in game theory, special game classes, measures of distributed efficiency, utility design, and online learning rules, all with the interpretation of using game theory as a prescriptive paradigm for distributed control design.
    • MOOC in the Arab world: a case study

      Alshahrani, Khalid; Ally, Mohamed (Routledge, 2016-12-19)
      Massive Open Online Courses (MOOCs) have been spreading and receiving attention worldwide in the last few years. Universities mainly in the USA led the trend in distributing online courses to interested students across the globe. The Middle East is no exception. Recently, the MOOC movement started to gain some popularity in this region. The end of year 2013 witnessed the beginning of the fi rst Arabic MOOC in the Arab World, namely Rwaq. What makes this initiative unique is that the course content is in Arabic, and presented by Arab lecturers to Arabic-speaking students.
    • Managing the change during e-learning integration in higher education: a case study from Saudi Arabia

      Alshahrani, Khalid; Ally, Mohamed (Routledge, 2016-12-19)
      Information and Communication Technologies (ICTs) that are already familiar components in business environments are fi nding their way into education at all levels in many parts of the world. Such technologies, however, disrupt education (Christensen, Horn and Johnson, 2008; Bonk, Lee, Kim and Lin, 2010) as they require changes in the teaching approaches and structure of institutions (McPherson and Nunes, 2008). People, on the other hand, can resist change because it challenges them and drives them out of their comfort zone (Latchem and Jung, 2010). Therefore, managing the change during the transition phase is crucial (Kotter, 1996) and a challenging task for any leader (Tibi and McLeod, 2010). Universities experience such challenges during the transition from a traditional way of teaching to more e-learning-based teaching and learning, and this chapter has taken one Saudi Arabian university as a case study.