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dc.contributor.authorSyaifudin, A. R Mohd
dc.contributor.authorYu, Paklam
dc.contributor.authorMukhopadhyay, Subhas Chandra
dc.contributor.authorGooneratne, Chinthaka Pasan
dc.contributor.authorKosel, Jürgen
dc.date.accessioned2015-08-04T07:13:25Z
dc.date.available2015-08-04T07:13:25Z
dc.date.issued2013-05
dc.identifier.isbn9781467346221
dc.identifier.issn10915281
dc.identifier.doi10.1109/I2MTC.2013.6555663
dc.identifier.urihttp://hdl.handle.net/10754/564714
dc.description.abstractNew types of planar interdigital sensors have been fabricated on Silicon/Silicon Dioxide (Si/SiO2) wafers. The sensors were coated with pre-cursor silica functionalized with APTES (3-aminopropyltrietoxysilane) at different thicknesses. All sensors were then immobilized with Polymyxin, B (PmB). PmB is an antimicrobial peptide produced by the Gram-positive bacterium-Bacillus, has been immobilized on the coated sensors because of its specific binding properties to endotoxin. Studies were conducted to analyze the effect of different thicknesses of coatings on the sensitivity and selectivity of the sensors. It was observed sensors coated with 3 layers of coating has better sensitivity and selectivity to the target molecules (endotoxin) compared to sensors with 5 layers of coating. The repeatability and stability of the coated sensors were tested by multiple standard endotoxin measurement and it was observed that the sensors give a good reproducibility and stability up to six continuous measurements before the coating degrades. © 2013 IEEE.
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)
dc.subjectAPTES
dc.subjectendotoxin
dc.subjectinterdigital
dc.subjectpolymyxin B
dc.subjectsilicon dioxide
dc.titleAnalysis of different coating thickness on new type of planar interdigital sensors for endotoxin detection
dc.typeConference Paper
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
dc.contributor.departmentElectrical Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.contributor.departmentSensing, Magnetism and Microsystems Lab
dc.identifier.journal2013 IEEE International Instrumentation and Measurement Technology Conference (I2MTC)
dc.conference.date6 May 2013 through 9 May 2013
dc.conference.name2013 IEEE International Instrumentation and Measurement Technology Conference: Instrumentation and Measurement for Life, I2MTC 2013
dc.conference.locationMinneapolis, MN
dc.contributor.institutionSchool of Engineering and Advanced Technology, Massey University, Palmerston North, New Zealand
kaust.personGooneratne, Chinthaka Pasan
kaust.personKosel, Jürgen


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