Enzyme-inspired functional surfactant for aerobic oxidation of activated alcohols to aldehydes in water
KAUST DepartmentAdvanced Nanofabrication, Imaging and Characterization Core Lab
Chemical Science Program
Imaging and Characterization Core Lab
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Online Publication Date2015-01-27
Print Publication Date2015-02-06
Permanent link to this recordhttp://hdl.handle.net/10754/564047
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AbstractWe describe an enzyme-inspired catalytic system based on a rationally designed multifunctional amphiphile. The resulting micelles feature metal-binding sites and stable free radical moieties as well as fluorous pockets that attract and preconcentrate molecular oxygen. In the presence of copper ions, the micelles effect chemoselective aerobic alcohol oxidation under ambient conditions in water, a transformation that is challenging to achieve nonenzymatically.
SponsorsThe authors are grateful to Dr. Virginia Unkefer and Ms. Sarah Almahdali for their help in preparing the manuscript, and to Prof. Mathias Christmann for a helpful discussion. This research was supported by King Abdullah University of Science and Technology.
PublisherAmerican Chemical Society (ACS)