Comparison of Artemisia annua bioactivities between traditional medicine and chemical extracts
Type
ArticleKAUST Department
Advanced Nanofabrication, Imaging and Characterization Core LabAnalytical Chemistry Core Lab
Analytical Core Lab
Biological and Environmental Sciences and Engineering (BESE) Division
Computational Bioscience Research Center (CBRC)
Core Labs
Design and Development Support
Imaging and Characterization Core Lab
Office of the VP
Date
2014-09-21Permanent link to this record
http://hdl.handle.net/10754/563488
Metadata
Show full item recordAbstract
The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of the plant were investigated. The results showed that water extracts of Artemisia annua from Jericho have stronger antibacterial activities than organic solvent extracts. In contrast, water and organic solvent extracts of the Artemisia annua from Egypt do not have anti-bacterial activity. Furthermore, while the methanol extract of EA displayed high anticancer affects, the water extract of Egypt and the extracts of Jericho did not show significant anticancer activity. Finally, the results showed that the methanol and water extracts of Jericho had the highest antioxidant activity, while the extracts of Egypt had none. The current results validate the scientific bases for the use of Artemisia annua in traditional medicine. In addition, our results suggest that the collection location of the Artemisia annua has an effect on its chemical composition and bioactivities. - See more at: http://www.eurekaselect.com/121416/article#sthash.2c2j9AoL.dpufCitation
Nageeb, A., Al-Tawashi, A., Emwas, A.-H., Al-Talla, Z., & Al-Rifai, N. (2014). Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts. Current Bioactive Compounds, 9(4), 324–332. doi:10.2174/157340720904140404151439Publisher
Bentham Science Publishers Ltd.Journal
Current Bioactive CompoundsPubMed ID
24761137PubMed Central ID
PMC3992861Additional Links
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992861https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992861
ae974a485f413a2113503eed53cd6c53
10.2174/157340720904140404151439
Scopus Count
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