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    Comparison of Artemisia annua bioactivities between traditional medicine and chemical extracts

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    Type
    Article
    Authors
    Nageeb, Ahmed
    Altawashi, Azza
    Emwas, Abdul-Hamid M.
    Al-Talla, Zeyad
    Al Rifai, Nahla
    KAUST Department
    Advanced Nanofabrication, Imaging and Characterization Core Lab
    Analytical Chemistry Core Lab
    Analytical Core Lab
    Biological and Environmental Sciences and Engineering (BESE) Division
    Computational Bioscience Research Center (CBRC)
    Core Labs
    Design and Development Support
    Imaging and Characterization Core Lab
    Office of the VP
    Date
    2014-09-21
    Permanent link to this record
    http://hdl.handle.net/10754/563488
    
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    Abstract
    The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of the plant were investigated. The results showed that water extracts of Artemisia annua from Jericho have stronger antibacterial activities than organic solvent extracts. In contrast, water and organic solvent extracts of the Artemisia annua from Egypt do not have anti-bacterial activity. Furthermore, while the methanol extract of EA displayed high anticancer affects, the water extract of Egypt and the extracts of Jericho did not show significant anticancer activity. Finally, the results showed that the methanol and water extracts of Jericho had the highest antioxidant activity, while the extracts of Egypt had none. The current results validate the scientific bases for the use of Artemisia annua in traditional medicine. In addition, our results suggest that the collection location of the Artemisia annua has an effect on its chemical composition and bioactivities. - See more at: http://www.eurekaselect.com/121416/article#sthash.2c2j9AoL.dpuf
    Citation
    Nageeb, A., Al-Tawashi, A., Emwas, A.-H., Al-Talla, Z., & Al-Rifai, N. (2014). Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts. Current Bioactive Compounds, 9(4), 324–332. doi:10.2174/157340720904140404151439
    Publisher
    Bentham Science Publishers Ltd.
    Journal
    Current Bioactive Compounds
    DOI
    10.2174/157340720904140404151439
    PubMed ID
    24761137
    PubMed Central ID
    PMC3992861
    Additional Links
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992861
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992861
    ae974a485f413a2113503eed53cd6c53
    10.2174/157340720904140404151439
    Scopus Count
    Collections
    Articles; Biological and Environmental Science and Engineering (BESE) Division; Analytical Chemistry Core Lab; Imaging and Characterization Core Lab; Computational Bioscience Research Center (CBRC)

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