• Login
    View Item 
    •   Home
    • Research
    • Articles
    • View Item
    •   Home
    • Research
    • Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    Effects of short-term niacin treatment on plasma lipoprotein concentrations in African green monkeys (Chlorocebus aethiops)

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Type
    Article
    Authors
    Chauke, Chesa G.
    Arieff, Zainunisha
    Kaur, Mandeep
    Seier, Jürgen V.
    KAUST Department
    Computational Bioscience Research Center (CBRC)
    Date
    2014-02-01
    Online Publication Date
    2014-02-01
    Print Publication Date
    2014-02
    Permanent link to this record
    http://hdl.handle.net/10754/563347
    
    Metadata
    Show full item record
    Abstract
    Niacin is the most effective drug available for raising levels of high-density lipoprotein (HDL) cholesterol. To evaluate its effects on plasma lipid concentrations, the authors administered a low dose of niacin to healthy, adult, female African green monkeys for 3 months. In the treated monkeys, low-density lipoprotein cholesterol concentrations decreased by 43% from baseline, whereas concentrations of HDL cholesterol and apolipoprotein A-I increased by 49% and 34%, respectively. The results suggest that in this primate model, a low dose of niacin can effectively increase concentrations of HDL cholesterol.©2014 Nature America, Inc. All rights reserved.
    Citation
    Chauke, C. G., Arieff, Z., Kaur, M., & Seier, J. V. (2014). Effects of short-term niacin treatment on plasma lipoprotein concentrations in African green monkeys (Chlorocebus aethiops). Lab Animal, 43(2), 58–62. doi:10.1038/laban.424
    Publisher
    Springer Nature
    Journal
    Lab Animal
    DOI
    10.1038/laban.424
    PubMed ID
    24451360
    ae974a485f413a2113503eed53cd6c53
    10.1038/laban.424
    Scopus Count
    Collections
    Articles; Computational Bioscience Research Center (CBRC)

    entitlement

    Related articles

    • Effect of niacin on high-density lipoprotein apolipoprotein A-I kinetics in statin-treated patients with type 2 diabetes mellitus.
    • Authors: Pang J, Chan DC, Hamilton SJ, Tenneti VS, Watts GF, Barrett PH
    • Issue date: 2014 Feb
    • Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials.
    • Authors: Birjmohun RS, Hutten BA, Kastelein JJ, Stroes ES
    • Issue date: 2005 Jan 18
    • The facts behind niacin.
    • Authors: Hochholzer W, Berg DD, Giugliano RP
    • Issue date: 2011 Oct
    • Efficacy and safety of combination of extended release niacin and atorvastatin in patients with low levels of high density lipoprotein cholesterol.
    • Authors: Harikrishnan S, Rajeev E, Tharakan JA, Titus T, Ajit Kumar VK, Sivasankaran S, Krishnamoorthy KM, Nair K
    • Issue date: 2008 May-Jun
    • Niacin and lipoprotein(a): facts, uncertainties, and clinical considerations.
    • Authors: Scanu AM, Bamba R
    • Issue date: 2008 Apr 17
    DSpace software copyright © 2002-2023  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.