Synthesis and characterization of bisoxazolines- and pybox-copper(II) complexes and their application in the coupling of α-carbonyls with functionalized amines
Type
ArticleAuthors
Jia, WeiguoLi, Dandan
Dai, Yuanchen
Zhang, Hui
Yan, Liqin
Sheng, Enhong
Wei, Yun
Mu, Xiaolong
Huang, Kuo-Wei

KAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionChemical Science Program
Homogeneous Catalysis Laboratory (HCL)
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2014Permanent link to this record
http://hdl.handle.net/10754/563220
Metadata
Show full item recordAbstract
Binuclear complexes [{(DMOX)CuCl}2(μ-Cl)2] (1), mononuclear complexes [(DMOX)CuBr2] (2) (DMOX = 4,5-dihydro-2-(4,5- dihydro-4,4-dimethyloxazol-2-yl)-4,4-dimethyloxazole) and the pybox Cu(ii) complex [(Dm-Pybox)CuBr2] (3) (Dm-Pybox = 2,6-bis[4′,4′- dimethyloxazolin-2′-yl]pyridine) were obtained by reactions of CuX 2 (X = Cl, Br) with DMOX and Dm-Pybox ligands, respectively. The molecular structures of 1, 2 and 3 have been determined by single-crystal X-ray diffraction analyses. The complexes 2 and 3 are efficient in catalyzing α-amination of ketones and esters through α-bromo carbonyl intermediate. The procedures are environmentally benign methods using molecular oxygen as an oxidant with water as the only byproduct. This journal is © the Partner Organisations 2014.Citation
Jia, W.-G., Li, D.-D., Dai, Y.-C., Zhang, H., Yan, L.-Q., Sheng, E.-H., … Huang, K.-W. (2014). Synthesis and characterization of bisoxazolines- and pybox-copper(ii) complexes and their application in the coupling of α-carbonyls with functionalized amines. Org. Biomol. Chem., 12(29), 5509–5516. doi:10.1039/c4ob01027bSponsors
This work was supported by the National Nature Science Foundation of China (21102004), and the Natural Science Foundation of the Anhui Higher Education Institutions of China (KJ2011A146), and the Project-sponsored by SRF for ROCS, SEM. K.-W. Huang acknowledges financial support from KAUST. We also thank Dr Richmond Lee for English polishing.Publisher
Royal Society of Chemistry (RSC)Journal
Organic & Biomolecular ChemistryRelations
Is Supplemented By:- [Dataset]
Jia, W.-G., Li, D.-D., Dai, Y.-C., Zhang, H., Yan, L.-Q., Sheng, E.-H., … Huang, K.-W. (2014). CCDC 973033: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/cc11nj5d. DOI: 10.5517/cc11nj5d HANDLE: 10754/624286 - [Dataset]
Jia, W.-G., Li, D.-D., Dai, Y.-C., Zhang, H., Yan, L.-Q., Sheng, E.-H., … Huang, K.-W. (2014). CCDC 973034: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/cc11nj6f. DOI: 10.5517/cc11nj6f HANDLE: 10754/624287 - [Dataset]
Jia, W.-G., Li, D.-D., Dai, Y.-C., Zhang, H., Yan, L.-Q., Sheng, E.-H., … Huang, K.-W. (2014). CCDC 978999: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/cc11vqm7. DOI: 10.5517/cc11vqm7 HANDLE: 10754/624301 - [Dataset]
Jia, W.-G., Li, D.-D., Dai, Y.-C., Zhang, H., Yan, L.-Q., Sheng, E.-H., … Huang, K.-W. (2014). CCDC 981179: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/cc11xzyw. DOI: 10.5517/cc11xzyw HANDLE: 10754/624303
ae974a485f413a2113503eed53cd6c53
10.1039/c4ob01027b