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Optimized fabrication protocols of microfluidic devices for X-ray analysis

dc.contributor.authorCatalano, Rossella
dc.contributor.authorPerozziello, Gerardo
dc.contributor.authorSimone, Giuseppina
dc.contributor.authorCandeloro, Patrizio
dc.contributor.authorGentile, Francesco T.
dc.contributor.authorColuccio, Maria Laura
dc.contributor.authorPardeo, Francesca
dc.contributor.authorBurghammer, Manfred C.
dc.contributor.authorCuda, Giovanni
dc.contributor.authorRiekel, Christian
dc.contributor.authorDi Fabrizio, Enzo M.
dc.date.accessioned2015-08-03T12:04:02Z
dc.date.available2015-08-03T12:04:02Z
dc.date.issued2014-07
dc.identifier.citationCatalano, R., Perozziello, G., Simone, G., Candeloro, P., Gentile, F., Coluccio, M. L., … Di Fabrizio, E. (2014). Optimized fabrication protocols of microfluidic devices for X-ray analysis. Microelectronic Engineering, 124, 13–16. doi:10.1016/j.mee.2014.04.016
dc.identifier.issn01679317
dc.identifier.doi10.1016/j.mee.2014.04.016
dc.identifier.urihttp://hdl.handle.net/10754/563007
dc.description.abstractMicrofluidics combined with X-ray scattering techniques allows probing conformational changes or assembly processes of biological materials. Our aim was to develop a highly X-ray transparent microfluidic cell for detecting small variations of X-ray scattering involved in such processes. We describe the fabrication of a polyimide microfluidic device based on a simple, reliable and inexpensive lamination process. The implemented microstructured features result in windows with optimized X-ray transmission. The microfluidic device was characterized by X-ray microbeam scattering at the ID13 beamline of the European Synchrotron Radiation Facility. © 2014 Elsevier B.V. All rights reserved.
dc.description.sponsorshipThis work was partially supported by the European project EUROMBR (grant agreement n. 608104), the project for Young Researchers financed from the Italian Ministry of Health (CUP J65C13001350001, project n. GR-2010-2311677) and the project FIRB "ReteNazionale di Ricerca sulle Nanoscienze ItalNanoNet" (cod. RBPR05JH2P_010, CUP B41J09000110005) granted to the nanotechnology laboratory of the Department of Experimental Medicine of the University of Catanzaro.
dc.publisherElsevier BV
dc.subjectLamination process
dc.subjectPolyimide microfluidic device
dc.subjectX-ray scattering
dc.titleOptimized fabrication protocols of microfluidic devices for X-ray analysis
dc.typeArticle
dc.contributor.departmentMaterial Science and Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalMicroelectronic Engineering
dc.contributor.institutionLab. BioNEM, University of Catanzaro, Catanzaro 88100, Italy
dc.contributor.institutionCRIB, Univerity of Naples (Federico II), Napoli 80125, Italy
dc.contributor.institutionEuropean Synchrotron Radiation Facility, Grenoble 38100, France
kaust.personDi Fabrizio, Enzo M.


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