An air-stable copper reagent for nucleophilic trifluoromethylthiolation of aryl halides
Type
ArticleAuthors
Weng, ZhiqiangHe, Weiming
Chen, Chaohuang
Lee, Richmond
Tan, Davin
Lai, Zhiping

Kong, Dedao
Yuan, Yaofeng
Huang, Kuo-Wei

KAUST Department
Advanced Membranes and Porous Materials Research CenterChemical Engineering Program
Chemical Science Program
Homogeneous Catalysis Laboratory (HCL)
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2012-12-12Online Publication Date
2012-12-12Print Publication Date
2013-01-28Permanent link to this record
http://hdl.handle.net/10754/562457
Metadata
Show full item recordAbstract
A series of copper(I) trifluoromethyl thiolate complexes have been synthesized from the reaction of CuF2 with Me3SiCF 3 and S8 (see scheme; Cu red, F green, N blue, S yellow). These air-stable complexes serve as reagents for the efficient conversion of a wide range of aryl halides into the corresponding aryl trifluoromethyl thioethers in excellent yields. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Citation
Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2012). An Air-Stable Copper Reagent for Nucleophilic Trifluoromethylthiolation of Aryl Halides. Angewandte Chemie International Edition, 52(5), 1548–1552. doi:10.1002/anie.201208432Sponsors
We thank Prof. John Hartwig for useful discussions. The financial support from National Natural Science Foundation of China (21072030) and Fuzhou University (022318) to Z.W. and KAUST to K.-W.H. are acknowledged.Publisher
WileyJournal
Angewandte ChemiePubMed ID
23239429Relations
Is Supplemented By:- [Dataset]
Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900614: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz752f. DOI: 10.5517/ccz752f HANDLE: 10754/624751 - [Dataset]
Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900613: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz751d. DOI: 10.5517/ccz751d HANDLE: 10754/624750 - [Dataset]
Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900612: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz750c. DOI: 10.5517/ccz750c HANDLE: 10754/624749 - [Dataset]
Weng, Z., He, W., Chen, C., Lee, R., Tan, D., Lai, Z., … Huang, K.-W. (2013). CCDC 900611: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccz74z9. DOI: 10.5517/ccz74z9 HANDLE: 10754/624748
ae974a485f413a2113503eed53cd6c53
10.1002/anie.201208432
Scopus Count
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