• Login
    View Item 
    •   Home
    • Research
    • Articles
    • View Item
    •   Home
    • Research
    • Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    Overview of errors in the reference sequence and annotation of Mycobacterium tuberculosis H37Rv, and variation amongst its isolates

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Type
    Article
    Authors
    Köser, Claudio U.
    Niemann, Stefan
    Summers, David K.
    Archer, John A.C. cc
    KAUST Department
    Computational Bioscience Research Center (CBRC)
    Date
    2012-06
    Permanent link to this record
    http://hdl.handle.net/10754/562208
    
    Metadata
    Show full item record
    Abstract
    Since its publication in 1998, the genome sequence of the Mycobacterium tuberculosis H37Rv laboratory strain has acted as the cornerstone for the study of tuberculosis. In this review we address some of the practical aspects that have come to light relating to the use of H37Rv throughout the past decade which are of relevance for the ongoing genomic and laboratory studies of this pathogen. These include errors in the genome reference sequence and its annotation, as well as the recently detected variation amongst isolates of H37Rv from different laboratories. © 2011 Elsevier B.V..
    Citation
    Köser, C. U., Niemann, S., Summers, D. K., & Archer, J. A. C. (2012). Overview of errors in the reference sequence and annotation of Mycobacterium tuberculosis H37Rv, and variation amongst its isolates. Infection, Genetics and Evolution, 12(4), 807–810. doi:10.1016/j.meegid.2011.06.011
    Sponsors
    Claudio U. Koser is a Gates Cambridge Scholar and received additional funding from the Cambridge Philosophical Society, the Cambridge European Trust and Clare Hall, Cambridge. We thank D. Collins, J. Parkhill, F. Spies, and S. Okamo for sharing some of their data. We are also grateful to S. Gagneux for proofreading this paper.
    Publisher
    Elsevier BV
    Journal
    Infection, Genetics and Evolution
    DOI
    10.1016/j.meegid.2011.06.011
    PubMed ID
    21723422
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.meegid.2011.06.011
    Scopus Count
    Collections
    Articles; Computational Bioscience Research Center (CBRC)

    entitlement

    Related articles

    • [Future prospects of molecular epidemiology in tuberculosis].
    • Authors: Matsumoto T, Iwamoto T
    • Issue date: 2009 Dec
    • Identification of moaA3 gene in patient isolates of Mycobacterium tuberculosis in Kerala, which is absent in M. tuberculosis H37Rv and H37Ra.
    • Authors: Sarojini S, Soman S, Radhakrishnan I, Mundayoor S
    • Issue date: 2005 Oct 4
    • Limitations of the Mycobacterium tuberculosis reference genome H37Rv in the detection of virulence-related loci.
    • Authors: O'Toole RF, Gautam SS
    • Issue date: 2017 Oct
    • What we can learn from the Mycobacterium tuberculosis genome sequencing projects.
    • Authors: Manabe YC, Dannenberg AM Jr, Bishai WR
    • Issue date: 2000 Feb
    • Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories.
    • Authors: Ioerger TR, Feng Y, Ganesula K, Chen X, Dobos KM, Fortune S, Jacobs WR Jr, Mizrahi V, Parish T, Rubin E, Sassetti C, Sacchettini JC
    • Issue date: 2010 Jul
    DSpace software copyright © 2002-2023  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.