Show simple item record

dc.contributor.authorWu, Linglin
dc.contributor.authorFalivene, Laura
dc.contributor.authorDrinkel, Emma E.
dc.contributor.authorGrant, Sharday
dc.contributor.authorLinden, Anthony
dc.contributor.authorCavallo, Luigi
dc.contributor.authorDorta, Reto
dc.date.accessioned2015-08-03T09:44:29Z
dc.date.available2015-08-03T09:44:29Z
dc.date.issued2012-02-06
dc.identifier.issn14337851
dc.identifier.doi10.1002/anie.201200206
dc.identifier.urihttp://hdl.handle.net/10754/562087
dc.description.abstractModus operandi: Catalytic access to the title compounds through a new asymmetric α-arylation protocol is reported (see scheme). These products are formed in good yields and excellent enantioselectivities by using a new and easily synthesized chiral N-heterocyclic carbene (NHC) ligand. Advanced DFT calculations reveal the properties of the NHC ligand and the mode of operation of the catalyst. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
dc.publisherWiley-Blackwell
dc.subjectasymmetric catalysis
dc.subjectN-heterocyclic carbenes
dc.subjectoxindoles
dc.subjectpalladium
dc.subjectsynthetic methods
dc.titleSynthesis of 3-fluoro-3-aryl oxindoles: Direct enantioselective α arylation of amides
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentKAUST Catalysis Center (KCC)
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Division
dc.contributor.departmentChemical Science Program
dc.identifier.journalAngewandte Chemie International Edition
dc.contributor.institutionOrganisch-Chemisches Institut, Universität Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland
dc.contributor.institutionDipartimento di Chimica, Università di Salerno, Via Ponte don Melillo, 84084 Fisciano, Italy
dc.contributor.institutionSchool of Chemistry and Biochemistry, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
kaust.personCavallo, Luigi
dc.relation.isSupplementedByWu, L., Falivene, L., Drinkel, E., Grant, S., Linden, A., Cavallo, L., & Dorta, R. (2012). CCDC 861317: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccxx8fh
dc.relation.isSupplementedByDOI:10.5517/ccxx8fh
dc.relation.isSupplementedByHANDLE:http://hdl.handle.net/10754/624669
dc.relation.isSupplementedByWu, L., Falivene, L., Drinkel, E., Grant, S., Linden, A., Cavallo, L., & Dorta, R. (2012). CCDC 861318: Experimental Crystal Structure Determination [Data set]. Cambridge Crystallographic Data Centre. https://doi.org/10.5517/ccxx8gj
dc.relation.isSupplementedByDOI:10.5517/ccxx8gj
dc.relation.isSupplementedByHANDLE:http://hdl.handle.net/10754/624670


This item appears in the following Collection(s)

Show simple item record