Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Center for Desert Agriculture
Desert Agriculture Initiative
Office of the VP
Embargo End Date2012-05-20
Permanent link to this recordhttp://hdl.handle.net/10754/562079
MetadataShow full item record
AbstractSmall, non-coding RNAs are a distinct class of regulatory RNAs in plants and animals that control a variety of biological processes. In plants, several classes of small RNAs with specific sizes and dedicated functions have evolved through a series of pathways. The major classes of small RNAs include microRNAs (miRNAs) and small interfering RNAs (siRNAs), which differ in their biogenesis. miRNAs control the expression of cognate target genes by binding to reverse complementary sequences, resulting in cleavage or translational inhibition of the target RNAs. siRNAs have a similar structure, function, and biogenesis as miRNAs but are derived from long double-stranded RNAs and can often direct DNA methylation at target sequences. Besides their roles in growth and development and maintenance of genome integrity, small RNAs are also important components in plant stress responses. One way in which plants respond to environmental stress is by modifying their gene expression through the activity of small RNAs. Thus, understanding how small RNAs regulate gene expression will enable researchers to explore the role of small RNAs in biotic and abiotic stress responses. This review focuses on the regulatory roles of plant small RNAs in the adaptive response to stresses. This article is part of a Special Issue entitled: Plant gene regulation in response to abiotic stress. © 2011 Elsevier B.V.
CitationKhraiwesh, B., Zhu, J.-K., & Zhu, J. (2012). Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1819(2), 137–148. doi:10.1016/j.bbagrm.2011.05.001
SponsorsThis work was supported by USDA and NIH grants to J.-K. Zhu and by National Science Foundation grants IOS0919745 and MCB0950242 to J. Zhu.
PubMed Central IDPMC3175014
- MicroRNAs with macro-effects on plant stress responses.
- Authors: Sunkar R
- Issue date: 2010 Oct
- The functions of plant small RNAs in development and in stress responses.
- Authors: Li S, Castillo-González C, Yu B, Zhang X
- Issue date: 2017 May
- Plant small RNAs: biogenesis, mode of action and their roles in abiotic stresses.
- Authors: Guleria P, Mahajan M, Bhardwaj J, Yadav SK
- Issue date: 2011 Dec
- Orthologous plant microRNAs: microregulators with great potential for improving stress tolerance in plants.
- Authors: Rajwanshi R, Chakraborty S, Jayanandi K, Deb B, Lightfoot DA
- Issue date: 2014 Dec
- Small RNAs as big players in plant abiotic stress responses and nutrient deprivation.
- Authors: Sunkar R, Chinnusamy V, Zhu J, Zhu JK
- Issue date: 2007 Jul