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dc.contributor.authorKhan, Hadayat Ullah
dc.contributor.authorJang, Junhyuk
dc.contributor.authorKim, Jangjoo
dc.contributor.authorKnoll, Wolfgang
dc.date.accessioned2015-08-03T09:04:38Z
dc.date.available2015-08-03T09:04:38Z
dc.date.issued2011-06
dc.identifier.citationKhan, H. U., Jang, J., Kim, J.-J., & Knoll, W. (2011). Effect of passivation on the sensitivity and stability of pentacene transistor sensors in aqueous media. Biosensors and Bioelectronics, 26(10), 4217–4221. doi:10.1016/j.bios.2011.03.031
dc.identifier.issn09565663
dc.identifier.pmid21546238
dc.identifier.doi10.1016/j.bios.2011.03.031
dc.identifier.urihttp://hdl.handle.net/10754/561788
dc.description.abstractCharge-detecting biosensors have recently become the focal point of biosensor research, especially research onto organic thin-film transistors (OTFTs), which combine compactness, a low cost, and fast and label-free detection to realize simple and stable in vivo diagnostic systems. We fabricated organic pentacene-based bottom-contact thin-film transistors with an ultra-thin insulating layer of a cyclized perfluoro polymer called CYTOP (Asahi Glass Co., Tokyo, Japan) on SiO2 for operation in aqueous media. The stability and sensitivity of these transistor sensors were examined in aqueous buffer media with solutions of variable pH levels after the passivation of perfluoro polymers with thicknesses ranging from 50 to 300nm. These transistor sensors were further modified with an ultra-thin film (5nm) functional layer for selective BSA/antiBSA detection in aqueous buffer media, demonstrating a detection capability as low as 500nM of concentrated antiBSA. The dissociation constant from the antiBSA detection results was 2.1×10-6M. Thus, this study represents a significant step forward in the development of organic electronics for a disposable and versatile chemical and bio-sensing platform. © 2011 Elsevier B.V.
dc.description.sponsorshipH.U.K. acknowledges the financial support from IRTG/1404 (funded by the DFG) and the Max-Planck Society (Germany). J.-J.K. acknowledges the WCU (R31-2008-000-10075-0) and BSR (R15-2008-006-01001-0) support through the NRF funded by the Ministry of Education, Science and Technology of Korea.
dc.publisherElsevier BV
dc.subjectAntiBSA detection
dc.subjectBioelectronics
dc.subjectEncapsulation effect
dc.subjectOTFT sensors
dc.subjectPH sensor
dc.titleEffect of passivation on the sensitivity and stability of pentacene transistor sensors in aqueous media
dc.typeArticle
dc.contributor.departmentMaterial Science and Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalBiosensors and Bioelectronics
dc.contributor.institutionMax-Planck-Institut for Polymerforschung, Ackermannweg 10, D-55128 Mainz, Germany
dc.contributor.institutionOLED Center, Department of Materials Science and Engineering, Seoul National University, Seoul, 151-744, South Korea
dc.contributor.institutionAustrian Institute of Technology (AIT) GmbH, Donau-City-Str. 1, 1220 Vienna, Austria
kaust.personKhan, Hadayat Ullah


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