• Login
    View Item 
    •   Home
    • Research
    • Articles
    • View Item
    •   Home
    • Research
    • Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    RNA-directed DNA methylation: Mechanisms and functions

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Type
    Article
    Authors
    Mahfouz, Magdy M. cc
    KAUST Department
    Biological and Environmental Science and Engineering (BESE) Division
    Bioscience Program
    Center for Desert Agriculture
    Laboratory for Genome Engineering
    Plant Science
    Plant Science Program
    Date
    2014-10-28
    Online Publication Date
    2014-10-28
    Print Publication Date
    2010-07
    Permanent link to this record
    http://hdl.handle.net/10754/561530
    
    Metadata
    Show full item record
    Abstract
    Epigenetic RNA based gene silencing mechanisms play a major role in genome stability and control of gene expression. Transcriptional gene silencing via RNA-directed DNA methylation (RdDM) guides the epigenetic regulation of the genome in response to disease states, growth, developmental and stress signals. RdDM machinery is composed of proteins that produce and modify 24-nt- long siRNAs, recruit the RdDM complex to genomic targets, methylate DNA and remodel chromatin. The final DNA methylation pattern is determined by either DNA methyltransferase alone or by the combined action of DNA methyltransferases and demethylases. The dynamic interaction between RdDM and demethylases may render the plant epigenome plastic to growth, developmental, and environmental cues. The epigenome plasticity may allow the plant genome to assume many epigenomes and to have the right epigenome at the right time in response to intracellular or extracellular stimuli. This review discusses recent advances in RdDM research and considers future perspectives.
    Citation
    Mahfouz, M. M. (2010). RNA-directed DNA methylation. Plant Signaling & Behavior, 5(7), 806–816. doi:10.4161/psb.5.7.11695
    Publisher
    Informa UK Limited
    Journal
    Plant Signaling & Behavior
    DOI
    10.4161/psb.5.7.11695
    PubMed ID
    20421728
    PubMed Central ID
    PMC3115029
    Additional Links
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115029
    ae974a485f413a2113503eed53cd6c53
    10.4161/psb.5.7.11695
    Scopus Count
    Collections
    Articles; Biological and Environmental Science and Engineering (BESE) Division; Bioscience Program; Plant Science Program; Center for Desert Agriculture

    entitlement

    Related articles

    • RNA-directed DNA methylation.
    • Authors: Zhang H, Zhu JK
    • Issue date: 2011 Apr
    • RNA-directed DNA methylation and demethylation in plants.
    • Authors: Chinnusamy V, Zhu JK
    • Issue date: 2009 Apr
    • Non-canonical RNA-directed DNA methylation.
    • Authors: Cuerda-Gil D, Slotkin RK
    • Issue date: 2016 Nov 3
    • [Advances in the RNA-directed DNA methylation in plants].
    • Authors: Fu LY, Liu ZQ, Bai YL
    • Issue date: 2006 Nov
    • RNA-Directed DNA Methylation: The Evolution of a Complex Epigenetic Pathway in Flowering Plants.
    • Authors: Matzke MA, Kanno T, Matzke AJ
    • Issue date: 2015
    DSpace software copyright © 2002-2022  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.