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    Nsite, NsiteH and NsiteM Computer Tools for Studying Tran-scription Regulatory Elements

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    Name:
    Bioinformatics-2015-Shahmuradov-bioinformatics_btv404.pdf
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    BNotes_NSITE_Sovovyev_Supplementary_1.doc
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    Type
    Article
    Authors
    Shahmuradov, Ilham
    Solovyev, Victor cc
    KAUST Department
    Computational Bioscience Research Center (CBRC)
    Computer Science Program
    Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
    Date
    2015-07-02
    Online Publication Date
    2015-07-02
    Print Publication Date
    2015-11-01
    Permanent link to this record
    http://hdl.handle.net/10754/559100
    
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    Abstract
    Summary: Gene transcription is mostly conducted through interactions of various transcription factors and their binding sites on DNA (regulatory elements, REs). Today, we are still far from understanding the real regulatory content of promoter regions. Computer methods for identification of REs remain a widely used tool for studying and understanding transcriptional regulation mechanisms. The Nsite, NsiteH and NsiteM programs perform searches for statistically significant (non-random) motifs of known human, animal and plant one-box and composite REs in a single genomic sequence, in a pair of aligned homologous sequences and in a set of functionally related sequences, respectively.
    Citation
    Nsite, NsiteH and NsiteM Computer Tools for Studying Tran-scription Regulatory Elements 2015:btv404 Bioinformatics
    Publisher
    Oxford University Press (OUP)
    Journal
    Bioinformatics
    DOI
    10.1093/bioinformatics/btv404
    PubMed ID
    26142184
    Additional Links
    http://bioinformatics.oxfordjournals.org/lookup/doi/10.1093/bioinformatics/btv404
    ae974a485f413a2113503eed53cd6c53
    10.1093/bioinformatics/btv404
    Scopus Count
    Collections
    Articles; Computer Science Program; Computational Bioscience Research Center (CBRC); Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

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