Nsite, NsiteH and NsiteM Computer Tools for Studying Tran-scription Regulatory Elements
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Type
ArticleKAUST Department
Computational Bioscience Research Center (CBRC)Computer Science Program
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Date
2015-07-02Online Publication Date
2015-07-02Print Publication Date
2015-11-01Permanent link to this record
http://hdl.handle.net/10754/559100
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Summary: Gene transcription is mostly conducted through interactions of various transcription factors and their binding sites on DNA (regulatory elements, REs). Today, we are still far from understanding the real regulatory content of promoter regions. Computer methods for identification of REs remain a widely used tool for studying and understanding transcriptional regulation mechanisms. The Nsite, NsiteH and NsiteM programs perform searches for statistically significant (non-random) motifs of known human, animal and plant one-box and composite REs in a single genomic sequence, in a pair of aligned homologous sequences and in a set of functionally related sequences, respectively.Citation
Nsite, NsiteH and NsiteM Computer Tools for Studying Tran-scription Regulatory Elements 2015:btv404 BioinformaticsPublisher
Oxford University Press (OUP)Journal
BioinformaticsPubMed ID
26142184ae974a485f413a2113503eed53cd6c53
10.1093/bioinformatics/btv404
Scopus Count
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