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    Enzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging

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    C5NR03065J.pdf
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    1.732Mb
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    PDF
    Description:
    Accepted Manuscript
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    Type
    Article
    Authors
    Fatieiev, Yevhen cc
    Croissant, Jonas G.
    Julfakyan, Khachatur cc
    Deng, Lin cc
    Anjum, Dalaver H. cc
    Gurinov, Andrei cc
    Khashab, Niveen M. cc
    KAUST Department
    Advanced Membranes and Porous Materials Research Center
    Chemical Science Program
    Electron Microscopy
    Entrepreneurship Center
    Imaging and Characterization Core Lab
    Investment Fund
    NMR
    Nanofabrication Core Lab
    Physical Science and Engineering (PSE) Division
    Smart Hybrid Materials (SHMs) lab
    Date
    2015
    Permanent link to this record
    http://hdl.handle.net/10754/558874
    
    Metadata
    Show full item record
    Abstract
    Non-aggregated dense bridged silsesquioxane (BS) nanoparticles based on nature-inspired oxamide bridges are shown to degrade in simulated biological media upon cleavage with endopeptidase. Fluorescent BS nanoprobes with incorporated fluorescein dyes were applied for in-vitro imaging in cancer cells.
    Citation
    Enzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging 2015 Nanoscale
    Publisher
    Royal Society of Chemistry (RSC)
    Journal
    Nanoscale
    DOI
    10.1039/C5NR03065J
    PubMed ID
    26165456
    Additional Links
    http://pubs.rsc.org/en/Content/ArticleLanding/2015/NR/C5NR03065J
    ae974a485f413a2113503eed53cd6c53
    10.1039/C5NR03065J
    Scopus Count
    Collections
    Nanofabrication Core Lab; Articles; Advanced Membranes and Porous Materials Research Center; Imaging and Characterization Core Lab; Physical Science and Engineering (PSE) Division; Controlled Release and Delivery Laboratory; Chemical Science Program

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