Enzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging
Type
ArticleAuthors
Fatieiev, Yevhen
Croissant, Jonas G.
Julfakyan, Khachatur

Deng, Lin

Anjum, Dalaver H.

Gurinov, Andrei

Khashab, Niveen M.

KAUST Department
Advanced Membranes and Porous Materials Research CenterChemical Science Program
Electron Microscopy
Entrepreneurship Center
Imaging and Characterization Core Lab
Investment Fund
NMR
Nanofabrication Core Lab
Physical Science and Engineering (PSE) Division
Smart Hybrid Materials (SHMs) lab
Date
2015Permanent link to this record
http://hdl.handle.net/10754/558874
Metadata
Show full item recordAbstract
Non-aggregated dense bridged silsesquioxane (BS) nanoparticles based on nature-inspired oxamide bridges are shown to degrade in simulated biological media upon cleavage with endopeptidase. Fluorescent BS nanoprobes with incorporated fluorescein dyes were applied for in-vitro imaging in cancer cells.Citation
Enzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging 2015 NanoscalePublisher
Royal Society of Chemistry (RSC)Journal
NanoscalePubMed ID
26165456Additional Links
http://pubs.rsc.org/en/Content/ArticleLanding/2015/NR/C5NR03065Jae974a485f413a2113503eed53cd6c53
10.1039/C5NR03065J
Scopus Count
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