Enzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging
Croissant, Jonas G.
Anjum, Dalaver H.
Khashab, Niveen M.
KAUST DepartmentAdvanced Membranes and Porous Materials Research Center
Chemical Science Program
Imaging and Characterization Core Lab
Nanofabrication Core Lab
Physical Sciences and Engineering (PSE) Division
Smart Hybrid Materials (SHMs) lab
Permanent link to this recordhttp://hdl.handle.net/10754/558874
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AbstractNon-aggregated dense bridged silsesquioxane (BS) nanoparticles based on nature-inspired oxamide bridges are shown to degrade in simulated biological media upon cleavage with endopeptidase. Fluorescent BS nanoprobes with incorporated fluorescein dyes were applied for in-vitro imaging in cancer cells.
CitationEnzymatically Degradable Hybrid Organic-Inorganic Bridged Silsesquioxane Nanoparticles for In-Vitro Imaging 2015 Nanoscale
PublisherRoyal Society of Chemistry (RSC)
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