Re-growth, morphogenesis and differentiation during starfish arm regeneration
AuthorsKhadra, Yousra Ben
Di Benedetto, Cristiano
Candia Carnevali, M. Daniela
Permanent link to this recordhttp://hdl.handle.net/10754/558682
MetadataShow full item record
AbstractThe red starfish Echinaster sepositus is an excellent model for studying arm regeneration processes following traumatic amputation. The initial repair phase was described in a previous paper in terms of the early cicatrisation phenomena, and tissue and cell involvement. In this work we attempt to provide a further comprehensive description of the later regenerative stages in this species. Here we present the results of a detailed microscopic and submicroscopic investigation of the long regenerative phase, which can be subdivided into two sub-phases: early and advanced regenerative phases. The early regenerative phase (1-6 weeks p.a.) is characterized by tissue rearrangement, morphogenetic processes and initial differentiation events (mainly neurogenesis and skeletogenesis). The advanced regenerative phase (after 6 weeks p.a.) is characterized by further differentiation processes (early myogenesis), and obvious morphogenesis and re-growth of the regenerate. As in other starfish, the regenerative process in E. sepositus is relatively slow in comparison with that of crinoids and many ophiuroids, which is usually interpreted as resulting mainly from size-related aspects and of the more conspicuous involvement of morphallactic processes. Light and electron microscopy analyses suggest that some of the amputated structures, such as muscles, are not able to replace their missing parts by directly regrowing them from the remaining tissues, whereas others tissues, such as the skeleton and the radial nerve cord, appear to undergo direct re-growth. The overall process is in agreement with the distalization-intercalation model proposed by Agata and co-workers (1). Further experiments are needed to confirm this hypothesis. This article is protected by copyright. All rights reserved.
CitationRe-growth, morphogenesis and differentiation during starfish arm regeneration 2015:n/a Wound Repair and Regeneration
JournalWound Repair and Regeneration
- Wound repair during arm regeneration in the red starfish Echinaster sepositus.
- Authors: Ben Khadra Y, Ferrario C, Di Benedetto C, Said K, Bonasoro F, Carnevali MD, Sugni M
- Issue date: 2015 Jul-Aug
- Fundamental aspects of arm repair phase in two echinoderm models.
- Authors: Ferrario C, Ben Khadra Y, Czarkwiani A, Zakrzewski A, Martinez P, Colombo G, Bonasoro F, Candia Carnevali MD, Oliveri P, Sugni M
- Issue date: 2018 Jan 15
- Further amputations of the tail in adult Triturus carnifex: contribution to the study on the nature of regenerated spinal cord.
- Authors: Margotta V
- Issue date: 2008 Jul-Sep
- An integrated view of asteroid regeneration: tissues, cells and molecules.
- Authors: Ben Khadra Y, Sugni M, Ferrario C, Bonasoro F, Varela Coelho A, Martinez P, Candia Carnevali MD
- Issue date: 2017 Oct
- Microscopic overview of crinoid regeneration.
- Authors: Candia Carnevali MD, Bonasoro F
- Issue date: 2001 Dec 15