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    Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing

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    Type
    Article
    Authors
    Zhou, Bingpu
    Xu, Wei
    Syed, Ahad
    Chau, Yeungyeung
    Chen, Longqing
    Siang, Basil Chew Joo
    Yassine, Omar cc
    Wu, Xiaoxiao
    Gao, Yibo
    Zhang, Jingxian
    Xiao, Xiao
    Kosel, Jürgen cc
    Zhang, Xixiang cc
    Yao, Zhaohui
    Wen, Weijia
    KAUST Department
    Advanced Nanofabrication, Imaging and Characterization Core Lab
    Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
    Electrical Engineering Program
    Imaging and Characterization Core Lab
    KAUST-HKUST Micro/Nanofluidic Joint Laboratory
    Material Science and Engineering Program
    Nanofabrication Core Lab
    Patterning
    Physical Science and Engineering (PSE) Division
    Sensing, Magnetism and Microsystems Lab
    Date
    2015
    Permanent link to this record
    http://hdl.handle.net/10754/347341
    
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    Abstract
    Magnetically functionalized PDMS-based micropillar arrays have been successfully designed, fabricated and implanted for controllable microfluidic mixing. The arrangement of PDMS micropillar arrays inside the microchannel can be flexibly controlled by an external magnetic field. As a consequence, the flow fields inside the microchannel can be regulated at will via magnetic activation conveniently. When a microchannel is implanted with such micropillar arrays, two microstreams can be mixed easily and controllably upon the simple application of an on/off magnetic signal. Mixing efficiencies based on micropillar arrays with different densities were investigated and compared. It was found that micropillar arrays with higher density (i.e. smaller pillar pitch) would render better mixing performance. Our microfluidic system is capable of generating highly reproducible results within many cycles of mixing/non-mixing conversion. We believe that the simple mixing-triggering method together with rapid and controllable mixing control will be extraordinarily valuable for various biological or chemical applications in the future. This journal is © The Royal Society of Chemistry 2015.
    Citation
    Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing 2015 Lab Chip
    Publisher
    Royal Society of Chemistry (RSC)
    Journal
    Lab Chip
    DOI
    10.1039/C5LC00173K
    PubMed ID
    25849640
    Additional Links
    http://pubs.rsc.org/en/Content/ArticleLanding/2015/LC/C5LC00173K
    ae974a485f413a2113503eed53cd6c53
    10.1039/C5LC00173K
    Scopus Count
    Collections
    Nanofabrication Core Lab; Articles; Imaging and Characterization Core Lab; Physical Science and Engineering (PSE) Division; Electrical Engineering Program; Material Science and Engineering Program; Sensing, Magnetism and Microsystems Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

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