Design and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing
KAUST DepartmentAdvanced Nanofabrication and Thin Film Core Lab
Physical Sciences and Engineering (PSE) Division
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Electrical Engineering Program
Materials Science and Engineering Program
Imaging and Characterization Core Lab
KAUST-HKUST Micro/Nanofluidic Joint Laboratory
Advanced Nanofabrication, Imaging and Characterization Core Lab
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AbstractMagnetically functionalized PDMS-based micropillar arrays have been successfully designed, fabricated and implanted for controllable microfluidic mixing. The arrangement of PDMS micropillar arrays inside the microchannel can be flexibly controlled by an external magnetic field. As a consequence, the flow fields inside the microchannel can be regulated at will via magnetic activation conveniently. When a microchannel is implanted with such micropillar arrays, two microstreams can be mixed easily and controllably upon the simple application of an on/off magnetic signal. Mixing efficiencies based on micropillar arrays with different densities were investigated and compared. It was found that micropillar arrays with higher density (i.e. smaller pillar pitch) would render better mixing performance. Our microfluidic system is capable of generating highly reproducible results within many cycles of mixing/non-mixing conversion. We believe that the simple mixing-triggering method together with rapid and controllable mixing control will be extraordinarily valuable for various biological or chemical applications in the future. This journal is © The Royal Society of Chemistry 2015.
CitationDesign and fabrication of magnetically functionalized flexible micropillar arrays for rapid and controllable microfluidic mixing 2015 Lab Chip
PublisherRoyal Society of Chemistry (RSC)
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