Show simple item record

dc.contributor.authorZourelidou, Melina
dc.contributor.authorAbsmanner, Birgit
dc.contributor.authorWeller, Benjamin
dc.contributor.authorBarbosa, Inês CR
dc.contributor.authorWillige, Björn C
dc.contributor.authorFastner, Astrid
dc.contributor.authorStreit, Verena
dc.contributor.authorPort, Sarah A
dc.contributor.authorColcombet, Jean
dc.contributor.authorde la Fuente van Bentem, Sergio
dc.contributor.authorHirt, Heribert
dc.contributor.authorKuster, Bernhard
dc.contributor.authorSchulze, Waltraud X
dc.contributor.authorHammes, Ulrich Z
dc.contributor.authorSchwechheimer, Claus
dc.date.accessioned2014-11-11T14:32:17Z
dc.date.available2014-11-11T14:32:17Z
dc.date.issued2014-06-19
dc.identifier.citationZourelidou M, Absmanner B, Weller B, Barbosa IC, Willige BC, et al. (2014) Auxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID. eLife 3. doi:10.7554/eLife.02860.
dc.identifier.issn2050084X
dc.identifier.pmid24948515
dc.identifier.doi10.7554/eLife.02860
dc.identifier.urihttp://hdl.handle.net/10754/334618
dc.description.abstractThe development and morphology of vascular plants is critically determined by synthesis and proper distribution of the phytohormone auxin. The directed cell-to-cell distribution of auxin is achieved through a system of auxin influx and efflux transporters. PIN-FORMED (PIN) proteins are proposed auxin efflux transporters, and auxin fluxes can seemingly be predicted based on the-in many cells-asymmetric plasma membrane distribution of PINs. Here, we show in a heterologous Xenopus oocyte system as well as in Arabidopsis thaliana inflorescence stems that PIN-mediated auxin transport is directly activated by D6 PROTEIN KINASE (D6PK) and PINOID (PID)/WAG kinases of the Arabidopsis AGCVIII kinase family. At the same time, we reveal that D6PKs and PID have differential phosphosite preferences. Our study suggests that PIN activation by protein kinases is a crucial component of auxin transport control that must be taken into account to understand auxin distribution within the plant.
dc.language.isoen
dc.publishereLife Sciences Publications, Ltd
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/
dc.titleAuxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentDesert Agriculture Initiative
dc.contributor.departmentHirt Lab
dc.contributor.departmentPlant Science
dc.contributor.departmentPlant Science Program
dc.identifier.journaleLife
dc.identifier.pmcidPMC4091124
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionDepartment of Plant Systems Biology, Technische Universitt Mnchen, Freising, Germany
dc.contributor.institutionDepartment of Cell Biology and Plant Biochemistry, Universitt Regensburg, Regensburg, Germany
dc.contributor.institutionUnit de Recherche en Gnomique Vgtale, Universit Evry, Evry, France
dc.contributor.institutionDepartment of Plant Molecular Biology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria
dc.contributor.institutionProteomics and Bioanalytics, Technische Universitt Mnchen, Freising, Germany
dc.contributor.institutionMax-Planck-Institute of Molecular Plant Physiology, Potsdam, Germany
dc.contributor.institutionPlant Systems Biology, Universitt Hohenheim, Hohenheim, Germany
dc.contributor.institutionSalk Institute for Biological Studies, La Jolla, United States
dc.contributor.institutionDepartment of Molecular Biology, Gttingen University Medical Center, Gttingen, Germany
dc.contributor.institutionSyngenta Seeds B.V, Enkhuizen, Netherlands
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)
kaust.personHirt, Heribert
refterms.dateFOA2018-06-13T16:01:14Z


Files in this item

Thumbnail
Name:
Article-eLife-Auxin_effl-2014.pdf
Size:
3.012Mb
Format:
PDF
Description:
Article - Full Text
Thumbnail
Name:
Supplement_1_-_eLife-Auxin_effl-2014.elife02860s002.xlsx
Size:
15.76Kb
Format:
Microsoft Excel 2007
Description:
Supplemental File 1

This item appears in the following Collection(s)

Show simple item record

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
Except where otherwise noted, this item's license is described as This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.