From link-prediction in brain connectomes and protein interactomes to the local-community-paradigm in complex networks.
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AbstractGrowth and remodelling impact the network topology of complex systems, yet a general theory explaining how new links arise between existing nodes has been lacking, and little is known about the topological properties that facilitate link-prediction. Here we investigate the extent to which the connectivity evolution of a network might be predicted by mere topological features. We show how a link/community-based strategy triggers substantial prediction improvements because it accounts for the singular topology of several real networks organised in multiple local communities - a tendency here named local-community-paradigm (LCP). We observe that LCP networks are mainly formed by weak interactions and characterise heterogeneous and dynamic systems that use self-organisation as a major adaptation strategy. These systems seem designed for global delivery of information and processing via multiple local modules. Conversely, non-LCP networks have steady architectures formed by strong interactions, and seem designed for systems in which information/energy storage is crucial.
CitationCannistraci CV, Alanis-Lobato G, Ravasi T (2013) From link-prediction in brain connectomes and protein interactomes to the local-community-paradigm in complex networks. Sci Rep 3. doi:10.1038/srep01613.
PublisherNature Publishing Group
PubMed Central IDPMC3619147
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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/3.0/
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- Authors: Chen JY, Sivachenko AY, Bell R, Kurschner C, Ota I, Sahasrabudhe S
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