Symbiotic adaptation drives genome streamlining of the cyanobacterial sponge symbiont "Candidatus Synechococcus pongiarum"
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Wong, Yue Him
Batang, Zenon B.
Al-Suwailem, Abdulaziz M.
Bajic, Vladimir B.
KAUST DepartmentCoastal and Marine Resources Core Lab
Computational Bioscience Research Center (CBRC)
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Applied Mathematics and Computational Science Program
Online Publication Date2014-04-01
Print Publication Date2014-04-01
Permanent link to this recordhttp://hdl.handle.net/10754/325461
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Abstract"Candidatus Synechococcus spongiarum" is a cyanobacterial symbiont widely distributed in sponges, but its functions at the genome level remain unknown. Here, we obtained the draft genome (1.66 Mbp, 90% estimated genome recovery) of "Ca. Synechococcus spongiarum" strain SH4 inhabiting the Red Sea sponge Carteriospongia foliascens. Phylogenomic analysis revealed a high dissimilarity between SH4 and free-living cyanobacterial strains. Essential functions, such as photosynthesis, the citric acid cycle, and DNA replication, were detected in SH4. Eukaryoticlike domains that play important roles in sponge-symbiont interactions were identified exclusively in the symbiont. However, SH4 could not biosynthesize methionine and polyamines and had lost partial genes encoding low-molecular-weight peptides of the photosynthesis complex, antioxidant enzymes, DNA repair enzymes, and proteins involved in resistance to environmental toxins and in biosynthesis of capsular and extracellular polysaccharides. These genetic modifications imply that "Ca. Synechococcus spongiarum" SH4 represents a low-light-adapted cyanobacterial symbiont and has undergone genome streamlining to adapt to the sponge's mild intercellular environment. 2014 Gao et al.
CitationGao Z-M, Wang Y, Tian R-M, Wong YH, Batang ZB, et al. (2014) Symbiotic Adaptation Drives Genome Streamlining of the Cyanobacterial Sponge Symbiont -Candidatus Synechococcus spongiarum.- mBio 5: e00079-14-e00079-14. doi:10.1128/mBio.00079-14.
PublisherAmerican Society for Microbiology
PubMed Central IDPMC3977351
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