Kwofie, Samuel K.
Bajic, Vladimir B.
KAUST DepartmentComputational Bioscience Research Center (CBRC)
Applied Mathematics and Computational Science Program
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Online Publication Date2010-09-29
Print Publication Date2011-01-01
Permanent link to this recordhttp://hdl.handle.net/10754/325450
MetadataShow full item record
AbstractProstate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount of data on PC. Several hundred genes are implicated in different stages of PC, which may help in developing diagnostic methods or even cures. In spite of this accumulated information, effective diagnostics and treatments remain evasive. We have developed Dragon Database of Genes associated with Prostate Cancer (DDPC) as an integrated knowledgebase of genes experimentally verified as implicated in PC. DDPC is distinctive from other databases in that (i) it provides pre-compiled biomedical text-mining information on PC, which otherwise require tedious computational analyses, (ii) it integrates data on molecular interactions, pathways, gene ontologies, gene regulation at molecular level, predicted transcription factor binding sites on promoters of PC implicated genes and transcription factors that correspond to these binding sites and (iii) it contains DrugBank data on drugs associated with PC. We believe this resource will serve as a source of useful information for research on PC. DDPC is freely accessible for academic and non-profit users via http://apps.sanbi.ac.za/ddpc/ and http://cbrc .kaust.edu.sa/ddpc/. The Author(s) 2010.
CitationMaqungo M, Kaur M, Kwofie SK, Radovanovic A, Schaefer U, et al. (2011) DDPC: Dragon Database of Genes associated with Prostate Cancer. Nucleic Acids Research 39: D980-D985. doi:10.1093/nar/gkq849.
PublisherOxford University Press (OUP)
JournalNucleic Acids Research
PubMed Central IDPMC3013759
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Dragon exploratory system on hepatitis C virus (DESHCV).
- Authors: Kwofie SK, Radovanovic A, Sundararajan VS, Maqungo M, Christoffels A, Bajic VB
- Issue date: 2011 Jun
- DDEC: Dragon database of genes implicated in esophageal cancer.
- Authors: Essack M, Radovanovic A, Schaefer U, Schmeier S, Seshadri SV, Christoffels A, Kaur M, Bajic VB
- Issue date: 2009 Jul 6
- Database for exploration of functional context of genes implicated in ovarian cancer.
- Authors: Kaur M, Radovanovic A, Essack M, Schaefer U, Maqungo M, Kibler T, Schmeier S, Christoffels A, Narasimhan K, Choolani M, Bajic VB
- Issue date: 2009 Jan
- DDESC: Dragon database for exploration of sodium channels in human.
- Authors: Sagar S, Kaur M, Dawe A, Seshadri SV, Christoffels A, Schaefer U, Radovanovic A, Bajic VB
- Issue date: 2008 Dec 20
- Drug repositioning for prostate cancer: using a data-driven approach to gain new insights.
- Authors: Wang Q, Xu R
- Issue date: 2017
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