The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode
Article - Full Text
Supplemental File 1
AuthorsCotton, James A
Lilley, Catherine J
Jones, Laura M
Reid, Adam J
Tsai, Isheng J
Cock, Peter J A
den Akker, Sebastian Eves-van
Palomares-Rius, Juan E
Jones, John T
Urwin, Peter E
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Computational Bioscience Research Center (CBRC)
Permanent link to this recordhttp://hdl.handle.net/10754/325273
MetadataShow full item record
AbstractBackground: Globodera pallida is a devastating pathogen of potato crops, making it one of the most economically important plant parasitic nematodes. It is also an important model for the biology of cyst nematodes. Cyst nematodes and root-knot nematodes are the two most important plant parasitic nematode groups and together represent a global threat to food security. Results: We present the complete genome sequence of G. pallida, together with transcriptomic data from most of the nematode life cycle, particularly focusing on the life cycle stages involved in root invasion and establishment of the biotrophic feeding site. Despite the relatively close phylogenetic relationship with root-knot nematodes, we describe a very different gene family content between the two groups and in particular extensive differences in the repertoire of effectors, including an enormous expansion of the SPRY domain protein family in G. pallida, which includes the SPRYSEC family of effectors. This highlights the distinct biology of cyst nematodes compared to the root-knot nematodes that were, until now, the only sedentary plant parasitic nematodes for which genome information was available. We also present in-depth descriptions of the repertoires of other genes likely to be important in understanding the unique biology of cyst nematodes and of potential drug targets and other targets for their control. Conclusions: The data and analyses we present will be central in exploiting post-genomic approaches in the development of much-needed novel strategies for the control of G. pallida and related pathogens. 2014 Cotton et al.; licensee BioMed Central Ltd.
CitationCotton JA, Lilley CJ, Jones LM, Kikuchi T, Reid AJ, et al. (2014) The genome and life-stage specific transcriptomes of Globodera pallida elucidate key aspects of plant parasitism by a cyst nematode. Genome Biology 15: R43. doi:10.1186/gb-2014-15-3-r43.
PubMed Central IDPMC4054857
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- The transcriptome of Nacobbus aberrans reveals insights into the evolution of sedentary endoparasitism in plant-parasitic nematodes.
- Authors: Eves-van den Akker S, Lilley CJ, Danchin EG, Rancurel C, Cock PJ, Urwin PE, Jones JT
- Issue date: 2014 Aug 13
- Analysis of the Transcriptome of the Infective Stage of the Beet Cyst Nematode, H. schachtii.
- Authors: Fosu-Nyarko J, Nicol P, Naz F, Gill R, Jones MG
- Issue date: 2016
- Genomic characterisation of the effector complement of the potato cyst nematode Globodera pallida.
- Authors: Thorpe P, Mantelin S, Cock PJ, Blok VC, Coke MC, Eves-van den Akker S, Guzeeva E, Lilley CJ, Smant G, Reid AJ, Wright KM, Urwin PE, Jones JT
- Issue date: 2014 Oct 23
- Identification and characterisation of a hyper-variable apoplastic effector gene family of the potato cyst nematodes.
- Authors: Eves-van den Akker S, Lilley CJ, Jones JT, Urwin PE
- Issue date: 2014 Sep
- Comparison of transcript profiles in different life stages of the nematode Globodera pallida under different host potato genotypes.
- Authors: Palomares-Rius JE, Hedley PE, Cock PJ, Morris JA, Jones JT, Vovlas N, Blok V
- Issue date: 2012 Dec