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    AuthorAlouini, Mohamed-Slim (1015)Schwingenschlögl, Udo (404)Cavallo, Luigi (375)Huang, Kuo-Wei (334)Eddaoudi, Mohamed (295)View MoreDepartmentPhysical Sciences and Engineering (PSE) Division (6194)Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division (4525)Biological and Environmental Sciences and Engineering (BESE) Division (2569)Electrical Engineering Program (1765)KAUST Catalysis Center (KCC) (1300)View MoreJournalScientific Reports (262)Applied Physics Letters (170)Journal of the American Chemical Society (135)Journal of Membrane Science (133)Combustion and Flame (129)View MoreKAUST Grant NumberBAS/1/1614-01-01 (45)OSR-2015-CRG4-2582 (39)URF/1/1976-02 (19)BAS/1/1606-01-01 (17)BAS/1/1351-01-01 (16)View MorePatent StatusPublished Application (376)Granted Patent (90)Provisional Application (1)PublisherElsevier BV (2444)Institute of Electrical and Electronics Engineers (IEEE) (1770)Wiley-Blackwell (1135)American Chemical Society (ACS) (1126)Springer Nature (974)View MoreSubjectCrystallography (577)Cell Parameters (576)Crystal Structure (576)Crystal System (576)Experimental 3D Coordinates (576)View MoreTypeArticle (11091)Conference Paper (2300)Dataset (676)Patent (467)Poster (309)View MoreYear (Issue Date)2019 (114)2018 (2157)2017 (2438)2016 (2402)2015 (2362)View MoreItem AvailabilityMetadata Only (7631)Open Access (7064)Embargoed (804)

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    Comment on: Isoniazid and rifampicin resistance-associated mutations in Mycobacterium tuberculosis isolates from Yangon, Myanmar: Implications for rapid molecular testing

    Köser, Claudio U.; Summers, David K.; Archer, John A.C. (Oxford University Press (OUP), 2010-12-21)
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    DFT elucidation of materials properties

    Bredas, Jean-Luc; Houk, Kendall N. (American Chemical Society (ACS), 2014-11-18)
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    Predictable annual aggregation of longnose parrotfish (Hipposcarus harid) in the Red Sea

    Spaet, Julia L.Y. (Springer Verlag, 2013-05-30)
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    Incorporating geostrophic wind information for improved space–time short-term wind speed forecasting

    Zhu, Xinxin; Bowman, Kenneth P.; Genton, Marc G. (Institute of Mathematical Statistics, 2014-09)
    Accurate short-term wind speed forecasting is needed for the rapid development and efficient operation of wind energy resources. This is, however, a very challenging problem. Although on the large scale, the wind speed is related to atmospheric pressure, temperature, and other meteorological variables, no improvement in forecasting accuracy was found by incorporating air pressure and temperature directly into an advanced space-time statistical forecasting model, the trigonometric direction diurnal (TDD) model. This paper proposes to incorporate the geostrophic wind as a new predictor in the TDD model. The geostrophic wind captures the physical relationship between wind and pressure through the observed approximate balance between the pressure gradient force and the Coriolis acceleration due to the Earth’s rotation. Based on our numerical experiments with data from West Texas, our new method produces more accurate forecasts than does the TDD model using air pressure and temperature for 1to 6-hour-ahead forecasts based on three different evaluation criteria. Furthermore, forecasting errors can be further reduced by using moving average hourly wind speeds to fit the diurnal pattern. For example, our new method obtains between 13.9% and 22.4% overall mean absolute error reduction relative to persistence in 2-hour-ahead forecasts, and between 5.3% and 8.2% reduction relative to the best previous space-time methods in this setting.
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    Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization Factors

    Joffré, Enrique; von Mentzer, Astrid; Abd El Ghany, Moataz; Oezguen, Numan; Savidge, Tor; Dougan, Gordon; Svennerholm, Ann-Mari; Sjöling, Åsa (American Society for Microbiology, 2015-01-15)
    Enterotoxigenic Escherichia coli (ETEC) is a significant cause of morbidity and mortality in the developing world. ETEC-mediated diarrhea is orchestrated by heat-labile toxin (LT) and heat-stable toxins (STp and STh), acting in concert with a repertoire of more than 25 colonization factors (CFs). LT, the major virulence factor, induces fluid secretion after delivery of a monomeric ADP-ribosylase (LTA) and its pentameric carrier B subunit (LTB). A study of ETEC isolates from humans in Brazil reported the existence of natural LT variants. In the present study, analysis of predicted amino acid sequences showed that the LT amino acid polymorphisms are associated with a geographically and temporally diverse set of 192 clinical ETEC strains and identified 12 novel LT variants. Twenty distinct LT amino acid variants were observed in the globally distributed strains, and phylogenetic analysis showed these to be associated with different CF profiles. Notably, the most prevalent LT1 allele variants were correlated with major ETEC lineages expressing CS1 + CS3 or CS2 + CS3, and the most prevalent LT2 allele variants were correlated with major ETEC lineages expressing CS5 + CS6 or CFA/I. LTB allele variants generally exhibited more-stringent amino acid sequence conservation (2 substitutions identified) than LTA allele variants (22 substitutions identified). The functional impact of LT1 and LT2 polymorphisms on virulence was investigated by measuring total-toxin production, secretion, and stability using GM1-enzyme-linked immunosorbent assays (GM1-ELISA) and in silico protein modeling. Our data show that LT2 strains produce 5-fold more toxin than LT1 strains (P < 0.001), which may suggest greater virulence potential for this genetic variant. Our data suggest that functionally distinct LT-CF variants with increased fitness have persisted during the evolution of ETEC and have spread globally.
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    Practical Switching-Based Hybrid FSO/RF Transmission and Its Performance Analysis

    Usman, Muneer; Hong-Chuan Yang; Alouini, Mohamed-Slim (Institute of Electrical and Electronics Engineers (IEEE), 2014-10)
    Hybrid free-space optical (FSO)/radio-frequency (RF) systems have emerged as a promising solution for high-data-rate wireless backhaul. We present and analyze a switching-based transmission scheme for the hybrid FSO/RF system. Specifically, either the FSO or RF link will be active at a certain time instance, with the FSO link enjoying a higher priority. We considered both a single-threshold case and a dual-threshold case for FSO link operation. Analytical expressions have been obtained for the outage probability, average bit error rate, and ergodic capacity for the resulting system. Numerical examples are presented to compare the performance of the hybrid scheme with the FSO-only scenario.
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    Effect of Gd doping and O deficiency on the Curie temperature of EuO

    Jutong, Nuttachai; Eckern, Ulrich; Mairoser, Thomas; Schwingenschlögl, Udo (Nature Publishing Group, 2015-01-27)
    The effect of Gd doping and O deficiency on the electronic structure, exchange interaction, and Curie temperature of EuO in the cubic and tetragonal phases is studied by means of density functional theory. For both defects, the Curie temperature is found to exhibit a distinct maximum as a function of the defect concentration. The existence of optimal defect concentrations is explained by the interplay of the on-site, RKKY, and superexchange contributions to the magnetism.
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    Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development

    Park, Myoungryoul; Yun, Kilyoung; Mohanty, Bijayalaxmi; Herath, Venura; Xu, Fuyu; Wijaya, Edward; Bajic, Vladimir B.; Yun, Songjoong; De Los Reyes, Benildo G. (Wiley-Blackwell, 2010-09-28)
    The R2R3-type OsMyb4 transcription factor of rice has been shown to play a role in the regulation of osmotic adjustment in heterologous overexpression studies. However, the exact composition and organization of its underlying transcriptional network has not been established to be a robust tool for stress tolerance enhancement by regulon engineering. OsMyb4 network was dissected based on commonalities between the global chilling stress transcriptome and the transcriptome configured by OsMyb4 overexpression. OsMyb4 controls a hierarchical network comprised of several regulatory sub-clusters associated with cellular defense and rescue, metabolism and development. It regulates target genes either directly or indirectly through intermediary MYB, ERF, bZIP, NAC, ARF and CCAAT-HAP transcription factors. Regulatory sub-clusters have different combinations of MYB-like, GCC-box-like, ERD1-box-like, ABRE-like, G-box-like, as1/ocs/TGA-like, AuxRE-like, gibberellic acid response element (GARE)-like and JAre-like cis-elements. Cold-dependent network activity enhanced cellular antioxidant capacity through radical scavenging mechanisms and increased activities of phenylpropanoid and isoprenoid metabolic processes involving various abscisic acid (ABA), jasmonic acid (JA), salicylic acid (SA), ethylene and reactive oxygen species (ROS) responsive genes. OsMyb4 network is independent of drought response element binding protein/C-repeat binding factor (DREB/CBF) and its sub-regulons operate with possible co-regulators including nuclear factor-Y. Because of its upstream position in the network hierarchy, OsMyb4 functions quantitatively and pleiotrophically. Supra-optimal expression causes misexpression of alternative targets with costly trade-offs to panicle development. © 2010 Blackwell Publishing Ltd.
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    Transpressional rupture of an unmapped fault during the 2010 Haiti earthquake

    Calais, Éric; Freed, Andrew M.; Mattioli, Glen S.; Amelung, Falk; Jonsson, Sigurjon; Jansma, Pamela E.; Hong, Sanghoon; Dixon, Timothy H.; Prépetit, Claude; Momplaisir, Roberte (Springer Nature, 2010-10-24)
    On 12 January 2010, a Mw7.0 earthquake struck the Port-au-Prince region of Haiti. The disaster killed more than 200,000 people and caused an estimated $8 billion in damages, about 100% of the country?s gross domestic product. The earthquake was initially thought to have ruptured the Enriquillog-Plantain Garden fault of the southern peninsula of Haiti, which is one of two main strike-slip faults inferred to accommodate the 2cmyr -1 relative motion between the Caribbean and North American plates. Here we use global positioning system and radar interferometry measurements of ground motion to show that the earthquake involved a combination of horizontal and contractional slip, causing transpressional motion. This result is consistent with the long-term pattern of strain accumulation in Hispaniola. The unexpected contractional deformation caused by the earthquake and by the pattern of strain accumulation indicates present activity on faults other than the Enriquillog-Plantain Garden fault. We show that the earthquake instead ruptured an unmapped north-dipping fault, called the Léogâne fault. The Léogâne fault lies subparallel tog-but is different fromg-the Enriquillog-Plantain Garden fault. We suggest that the 2010 earthquake may have activated the southernmost front of the Haitian fold-and-thrust belt as it abuts against the Enriquillog-Plantain Garden fault. As the Enriquillog-Plantain Garden fault did not release any significant accumulated elastic strain, it remains a significant seismic threat for Haiti and for Port-au-Prince in particular. © 2010 Macmillan Publishers Limited. All rights reserved.
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    Electronic effects of ruthenium-catalyzed [3+2]-cycloaddition of alkynes and azides

    Hou, Duenren; Kuan, Tingchun; Li, YuKai; Lee, Richmond; Huang, Kuo-Wei (Elsevier BV, 2010-11)
    A combined experimental and theoretical study of ruthenium-catalyzed azide-alkyne cycloaddition (RuAAC) reactions is presented and various electronic analyses were conducted to provide a basis in understanding the observed regioselectivity of the 1,2,3-triazole products. Computational studies using density functional theory (DFT) and atoms in molecules quantum theory (AIM) further yield fresh details on the electronic factors that determine the regioselectivity in the RuAAC. It is found that the formation of 1,2,3-triazole products is irreversible and from the Hammett study, the pathway involving a vinyl cationic intermediate is ruled out. The electronic effect favors the formation of 5-electron-donating-group substituted-1,2,3-trizoles. © 2010 Elsevier Ltd. All rights reserved.
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