Characterization of solid UV cross-linked PEGDA for biological applications

Abstract
This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.

Citation
Castro D, Ingram P, Kodzius R, Conchouso D, Yoon E, et al. (2013) Characterization of solid UV cross-linked PEGDA for biological applications. 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). doi:10.1109/MEMSYS.2013.6474277.

Publisher
Institute of Electrical and Electronics Engineers (IEEE)

Journal
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)

Conference/Event Name
IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013

DOI
10.1109/MEMSYS.2013.6474277

Additional Links
http://ieeexplore.ieee.org/lpdocs/epic03/wrapper.htm?arnumber=6474277http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6474277

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