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dc.contributor.authorBougot-Robin, Kristelle
dc.contributor.authorAustin, H. Robert
dc.contributor.authorBenisty, Henri
dc.contributor.authorHsing, I-Ming
dc.contributor.authorKodzius, Rimantas
dc.contributor.authorLi, Shunbo
dc.contributor.authorWen, Weijia
dc.contributor.authorZhang, Yinghua
dc.date.accessioned2013-10-20T11:10:00Z
dc.date.available2013-10-20T11:10:00Z
dc.date.issued2013-10-20
dc.identifier.citation"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensing
dc.identifier.urihttp://hdl.handle.net/10754/303701
dc.description.abstractResonant techniques are of wide interest to detect variation of effective refractive index at a chip surface. Both Surface Plasmon Resonance (SPR) and dielectric resonant waveguide (RWGs) can be exploited. Through their design, RWGs allow more flexibility (size of the biomolecule to detect, detection angle…). Using specially designed RWG “Peak-tracking chip”, we propose to use spatial information from a simple monochromatic picture as a new label-free bioarray technique. We discuss robustness, sensitivity, multiplex detection, fluidic integration of the technique and illustrate it through bulk refractive index sensing as well as specific recognition of DNA fragment from gyrase A.
dc.description.sponsorshipHKUST Special research fund initiative SRFIEG01; Hong-Kong government under the project SEG HKUST 10
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.relation.urlhttp://www.rsc.org/images/loc/2012/pdf/T.7.160.pdf
dc.rightsArchived with thanks to RSC
dc.subjectBioarray imaging
dc.subjectlabel-free
dc.subjectrefractive index sensing
dc.subjectresonance
dc.subjectgrating
dc.subject.meshComputer Simulation
dc.subject.meshDNA
dc.subject.meshGlycerol
dc.subject.meshRefractometry
dc.subject.meshSurface Plasmon Resonance
dc.subject.meshWater
dc.subject.meshComputer Simulation
dc.subject.meshDNA
dc.subject.meshGlycerol
dc.subject.meshRefractometry
dc.subject.meshSurface Plasmon Resonance
dc.subject.meshWater
dc.title"Peak-tracking chip" (PTC) for bulk refractive index sensing and bioarray sensing
dc.typeArticle
dc.contributor.departmentComputational Bioscience Research Center (CBRC)
dc.identifier.journalMicroTAS
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionThe Hong Kong University of Science and Technology (HKUST)
dc.contributor.affiliationKing Abdullah University of Science and Technology (KAUST)
refterms.dateFOA2018-06-14T06:37:28Z


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