Hepatitis C Virus: Virology and Genotypes

Handle URI:
http://hdl.handle.net/10754/627646
Title:
Hepatitis C Virus: Virology and Genotypes
Authors:
Abdelaziz, Ahmed
Abstract:
Hepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. HCV genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Earth Science and Engineering Program
Citation:
Aziz AA (2018) Hepatitis C Virus. Hepatitis C in Developing Countries: 3–11. Available: http://dx.doi.org/10.1016/B978-0-12-803233-6.00001-1.
Publisher:
Elsevier
Journal:
Hepatitis C in Developing Countries
Issue Date:
1-Dec-2017
DOI:
10.1016/B978-0-12-803233-6.00001-1
Type:
Book Chapter
Additional Links:
http://www.sciencedirect.com/science/article/pii/3-s2.0-B9780128032336000011
Appears in Collections:
Physical Sciences and Engineering (PSE) Division; Earth Science and Engineering Program; Book Chapters

Full metadata record

DC FieldValue Language
dc.contributor.authorAbdelaziz, Ahmeden
dc.date.accessioned2018-04-25T06:14:23Z-
dc.date.available2018-04-25T06:14:23Z-
dc.date.issued2017-12-01en
dc.identifier.citationAziz AA (2018) Hepatitis C Virus. Hepatitis C in Developing Countries: 3–11. Available: http://dx.doi.org/10.1016/B978-0-12-803233-6.00001-1.en
dc.identifier.doi10.1016/B978-0-12-803233-6.00001-1en
dc.identifier.urihttp://hdl.handle.net/10754/627646-
dc.description.abstractHepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. HCV genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.en
dc.publisherElsevieren
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/3-s2.0-B9780128032336000011en
dc.subjectCirrhosisen
dc.subjectGenotypesen
dc.subjectHepatitis C virusen
dc.subjectHepatocellular carcinomaen
dc.titleHepatitis C Virus: Virology and Genotypesen
dc.typeBook Chapteren
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentEarth Science and Engineering Programen
dc.identifier.journalHepatitis C in Developing Countriesen
kaust.authorAbdelaziz, Ahmeden
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