Bio-Inspired Carbon Monoxide Sensors with Voltage-Activated Sensitivity

Handle URI:
http://hdl.handle.net/10754/625847
Title:
Bio-Inspired Carbon Monoxide Sensors with Voltage-Activated Sensitivity
Authors:
Savagatrup, Suchol; Schroeder, Vera; He, Xin ( 0000-0001-7009-2826 ) ; Lin, Sibo; He, Maggie; Yassine, Omar ( 0000-0002-0117-8017 ) ; Salama, Khaled N. ( 0000-0001-7742-1282 ) ; Zhang, Xixiang ( 0000-0002-3478-6414 ) ; Swager, Timothy M. ( 0000-0002-3577-0510 )
Abstract:
Carbon monoxide (CO) outcompetes oxygen when binding to the iron center of hemeproteins, leading to a reduction in blood oxygen level and acute poisoning. Harvesting the strong specific interaction between CO and the iron porphyrin provides a highly selective and customizable sensor. We report the development of chemiresistive sensors with voltage-activated sensitivity for the detection of CO comprising iron porphyrin and functionalized single-walled carbon nanotubes (F-SWCNTs). Modulation of the gate voltage offers a predicted extra dimension for sensing. Specifically, the sensors show a significant increase in sensitivity toward CO when negative gate voltage is applied. The dosimetric sensors are selective to ppm levels of CO and functional in air. UV/Vis spectroscopy, differential pulse voltammetry, and density functional theory reveal that the in situ reduction of FeIII to FeII enhances the interaction between the F-SWCNTs and CO. Our results illustrate a new mode of sensors wherein redox active recognition units are voltage-activated to give enhanced and highly specific responses.
KAUST Department:
Physical Sciences and Engineering (PSE) Division; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division; Sensors Lab
Citation:
Savagatrup S, Schroeder V, He X, Lin S, He M, et al. (2017) Bio-Inspired Carbon Monoxide Sensors with Voltage-Activated Sensitivity. Angewandte Chemie International Edition. Available: http://dx.doi.org/10.1002/anie.201707491.
Publisher:
Wiley-Blackwell
Journal:
Angewandte Chemie International Edition
KAUST Grant Number:
CRF-2015-SENSORS-2719
Issue Date:
27-Sep-2017
DOI:
10.1002/anie.201707491; 10.1002/ange.201707491
Type:
Article
ISSN:
1433-7851
Sponsors:
This work was supported by the KAUST sensor project CRF-2015-SENSORS-2719 and the Army Research Office through the Institute for Soldier Nanotechnologies and the National Science Foundation (DMR-1410718). S.L. was supported by an F32 Ruth L. Kirschstein National Research Service Award. M.H. was supported by NIH Training Grant T32ES007020. We thank Dr. Lionel Moh for the designs of the substrates for our sensors and Dr. Joseph Walish for fabricating the gas enclosures.
Additional Links:
http://onlinelibrary.wiley.com/doi/10.1002/anie.201707491/full
Appears in Collections:
Articles; Physical Sciences and Engineering (PSE) Division; Sensors Lab; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

Full metadata record

DC FieldValue Language
dc.contributor.authorSavagatrup, Sucholen
dc.contributor.authorSchroeder, Veraen
dc.contributor.authorHe, Xinen
dc.contributor.authorLin, Siboen
dc.contributor.authorHe, Maggieen
dc.contributor.authorYassine, Omaren
dc.contributor.authorSalama, Khaled N.en
dc.contributor.authorZhang, Xixiangen
dc.contributor.authorSwager, Timothy M.en
dc.date.accessioned2017-10-11T05:46:47Z-
dc.date.available2017-10-11T05:46:47Z-
dc.date.issued2017-09-27en
dc.identifier.citationSavagatrup S, Schroeder V, He X, Lin S, He M, et al. (2017) Bio-Inspired Carbon Monoxide Sensors with Voltage-Activated Sensitivity. Angewandte Chemie International Edition. Available: http://dx.doi.org/10.1002/anie.201707491.en
dc.identifier.issn1433-7851en
dc.identifier.doi10.1002/anie.201707491en
dc.identifier.doi10.1002/ange.201707491en
dc.identifier.urihttp://hdl.handle.net/10754/625847-
dc.description.abstractCarbon monoxide (CO) outcompetes oxygen when binding to the iron center of hemeproteins, leading to a reduction in blood oxygen level and acute poisoning. Harvesting the strong specific interaction between CO and the iron porphyrin provides a highly selective and customizable sensor. We report the development of chemiresistive sensors with voltage-activated sensitivity for the detection of CO comprising iron porphyrin and functionalized single-walled carbon nanotubes (F-SWCNTs). Modulation of the gate voltage offers a predicted extra dimension for sensing. Specifically, the sensors show a significant increase in sensitivity toward CO when negative gate voltage is applied. The dosimetric sensors are selective to ppm levels of CO and functional in air. UV/Vis spectroscopy, differential pulse voltammetry, and density functional theory reveal that the in situ reduction of FeIII to FeII enhances the interaction between the F-SWCNTs and CO. Our results illustrate a new mode of sensors wherein redox active recognition units are voltage-activated to give enhanced and highly specific responses.en
dc.description.sponsorshipThis work was supported by the KAUST sensor project CRF-2015-SENSORS-2719 and the Army Research Office through the Institute for Soldier Nanotechnologies and the National Science Foundation (DMR-1410718). S.L. was supported by an F32 Ruth L. Kirschstein National Research Service Award. M.H. was supported by NIH Training Grant T32ES007020. We thank Dr. Lionel Moh for the designs of the substrates for our sensors and Dr. Joseph Walish for fabricating the gas enclosures.en
dc.publisherWiley-Blackwellen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1002/anie.201707491/fullen
dc.rightsThis is the peer reviewed version of the following article: Bio-Inspired Carbon Monoxide Sensors with Voltage-Activated Sensitivity, which has been published in final form at http://doi.org/10.1002/anie.201707491. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.en
dc.subjectSensorsen
dc.subjectCarbon monoxideen
dc.subjectCarbon nanotubesen
dc.subjectIron Porphyrinen
dc.subjectVoltage-activateden
dc.titleBio-Inspired Carbon Monoxide Sensors with Voltage-Activated Sensitivityen
dc.typeArticleen
dc.contributor.departmentPhysical Sciences and Engineering (PSE) Divisionen
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Divisionen
dc.contributor.departmentSensors Laben
dc.identifier.journalAngewandte Chemie International Editionen
dc.eprint.versionPost-printen
dc.contributor.institutionDepartment of Chemistry and Institute for Soldier Nanotechnologies; Massachusetts Institute of Technology; 77 Massachusetts Avenue Cambridge Massachusetts 02139 USAen
kaust.authorHe, Xinen
kaust.authorYassine, Omaren
kaust.authorSalama, Khaled N.en
kaust.authorZhang, Xixiangen
kaust.grant.numberCRF-2015-SENSORS-2719en
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