Enteric Infections Circulating during Hajj Seasons, 2011–2013

Handle URI:
http://hdl.handle.net/10754/625835
Title:
Enteric Infections Circulating during Hajj Seasons, 2011–2013
Authors:
Abd El Ghany, Moataz; Alsomali, Mona Ismael Ibrahim ( 0000-0003-2205-2146 ) ; Almasri, Malak; Padron Regalado, Eriko; Naeem, Raeece ( 0000-0003-1734-1007 ) ; Tukestani, AbdulHafeez; Asiri, Abdullah; Hill-Cawthorne, Grant A.; Pain, Arnab ( 0000-0002-1755-2819 ) ; Memish, Ziad A.
Abstract:
Hajj, the annual Muslim pilgrimage to Mecca, Saudi Arabia, is a unique mass gathering event that raises public health concerns in the host country and globally. Although gastroenteritis and diarrhea are common among Hajj pilgrims, the microbial etiologies of these infections are unknown. We collected 544 fecal samples from pilgrims with medically attended diarrheal illness from 40 countries during the 2011-2013 Hajj seasons and screened the samples for 16 pathogens commonly associated with diarrheal infections. Bacteria were the main agents detected, in 82.9% of the 228 positive samples, followed by viral (6.1%) and parasitic (5.3%) agents. Salmonella spp., Shigella/enteroinvasive Escherichia coli, and enterotoxigenic E. coli were the main pathogens associated with severe symptoms. We identified genes associated with resistance to third-generation cephalosporins approximate to 40% of Salmonella- and E. coli-positive samples. Hajj-associated foodborne infections pose a major public health risk through the emergence and transmission of antimicrobial drug-resistant bacteria.
KAUST Department:
King Abdullah University of Science and Technology, Thuwal, , Saudi Arabia
Citation:
Abd El Ghany M, Alsomali M, Almasri M, Regalado EP, Naeem R, et al. (2017) Enteric Infections Circulating during Hajj Seasons, 2011–2013. Emerging Infectious Diseases 23. Available: http://dx.doi.org/10.3201/eid2310.161642.
Publisher:
Centers for Disease Control and Prevention (CDC)
Journal:
Emerging Infectious Diseases
KAUST Grant Number:
BAS/1/1020-01-01
Issue Date:
13-Sep-2017
DOI:
10.3201/eid2310.161642
Type:
Article
ISSN:
1080-6040; 1080-6059
Sponsors:
This work was supported by the Saudi Ministry of Health (Z.M.) and King Abdullah University of Science and Technology (faculty baseline funding [BAS/1/1020-01-01] to A.P.), and Marie Bashir Institute and Sydney Medical School Foundation (M.A. and G.H.).
Additional Links:
https://wwwnc.cdc.gov/eid/article/23/10/16-1642_article
Appears in Collections:
Articles

Full metadata record

DC FieldValue Language
dc.contributor.authorAbd El Ghany, Moatazen
dc.contributor.authorAlsomali, Mona Ismael Ibrahimen
dc.contributor.authorAlmasri, Malaken
dc.contributor.authorPadron Regalado, Erikoen
dc.contributor.authorNaeem, Raeeceen
dc.contributor.authorTukestani, AbdulHafeezen
dc.contributor.authorAsiri, Abdullahen
dc.contributor.authorHill-Cawthorne, Grant A.en
dc.contributor.authorPain, Arnaben
dc.contributor.authorMemish, Ziad A.en
dc.date.accessioned2017-10-09T09:03:13Z-
dc.date.available2017-10-09T09:03:13Z-
dc.date.issued2017-09-13en
dc.identifier.citationAbd El Ghany M, Alsomali M, Almasri M, Regalado EP, Naeem R, et al. (2017) Enteric Infections Circulating during Hajj Seasons, 2011–2013. Emerging Infectious Diseases 23. Available: http://dx.doi.org/10.3201/eid2310.161642.en
dc.identifier.issn1080-6040en
dc.identifier.issn1080-6059en
dc.identifier.doi10.3201/eid2310.161642en
dc.identifier.urihttp://hdl.handle.net/10754/625835-
dc.description.abstractHajj, the annual Muslim pilgrimage to Mecca, Saudi Arabia, is a unique mass gathering event that raises public health concerns in the host country and globally. Although gastroenteritis and diarrhea are common among Hajj pilgrims, the microbial etiologies of these infections are unknown. We collected 544 fecal samples from pilgrims with medically attended diarrheal illness from 40 countries during the 2011-2013 Hajj seasons and screened the samples for 16 pathogens commonly associated with diarrheal infections. Bacteria were the main agents detected, in 82.9% of the 228 positive samples, followed by viral (6.1%) and parasitic (5.3%) agents. Salmonella spp., Shigella/enteroinvasive Escherichia coli, and enterotoxigenic E. coli were the main pathogens associated with severe symptoms. We identified genes associated with resistance to third-generation cephalosporins approximate to 40% of Salmonella- and E. coli-positive samples. Hajj-associated foodborne infections pose a major public health risk through the emergence and transmission of antimicrobial drug-resistant bacteria.en
dc.description.sponsorshipThis work was supported by the Saudi Ministry of Health (Z.M.) and King Abdullah University of Science and Technology (faculty baseline funding [BAS/1/1020-01-01] to A.P.), and Marie Bashir Institute and Sydney Medical School Foundation (M.A. and G.H.).en
dc.publisherCenters for Disease Control and Prevention (CDC)en
dc.relation.urlhttps://wwwnc.cdc.gov/eid/article/23/10/16-1642_articleen
dc.rightsEmerging Infectious Diseases is an open access journal in the public domain. All content is freely available without charge to the user or his/her institution. In accordance with the Budapest Open Access Initiative definition of Open Access, users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. Because the journal is in the public domain, its usage policy also conforms to conditions set for by Creative Commons.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.titleEnteric Infections Circulating during Hajj Seasons, 2011–2013en
dc.typeArticleen
dc.contributor.departmentKing Abdullah University of Science and Technology, Thuwal, , Saudi Arabiaen
dc.identifier.journalEmerging Infectious Diseasesen
dc.eprint.versionPublisher's Version/PDFen
dc.contributor.institutionUniversity of Sydney, , Australiaen
dc.contributor.institutionSaudi Arabia Ministry of Health, Riyadh, , Saudi Arabiaen
dc.contributor.institutionHokkaido University, Sapporo, , Japanen
dc.contributor.institutionEmory University, Atlanta, GA, , United Statesen
dc.contributor.institutionAlfaisal University, Riyadh, , Saudi Arabiaen
kaust.authorAbd El Ghany, Moatazen
kaust.authorAlsomali, Mona Ismael Ibrahimen
kaust.authorPadron Regalado, Erikoen
kaust.authorNaeem, Raeeceen
kaust.authorPain, Arnaben
kaust.grant.numberBAS/1/1020-01-01en
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